Results 211 to 220 of about 14,369,746 (295)
Abstract Background and aims Data on the presence of new psychoactive substances (NPS) mainly originate from drug‐checking, law enforcement and wastewater analysis sources, while data on NPS poisonings are scarce. In Europe, the documented incidence rate of NPS poisonings is highest in the Netherlands.
Johanna J. Nugteren‐van Lonkhuyzen +5 more
wiley +1 more source
Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm
Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley +1 more source
Methamphetamine self-administration in humans during D-amphetamine maintenance. [PDF]
Pike E +4 more
europepmc +1 more source
A pharmacological profiling of 58 synthetic stimulants of various classes at dopamine, norepinephrine, and serotonin transporters and the 5‐HT2A receptor, most showing distinct class‐dependent profiles, with some indicating a high abuse potential. Background and Purpose New psychoactive substances (NPSs) often emerge on the illicit drug market with ...
Darta Stalberga +9 more
wiley +1 more source
Variability in paralimbic dopamine signaling correlates with subjective responses to d-amphetamine. [PDF]
Smith CT +4 more
europepmc +1 more source
Impact of Donor Substance Use on Outcomes Following Pancreas Transplantation
ABSTRACT Background Donor substance use is considered by many a risk factor for poor outcomes following pancreas transplantation, yet little is known regarding the impact of donor substance use on actual outcomes. This study aimed to determine the impact of substance use, particularly cocaine, on early and late outcomes following pancreas ...
Sarah Huber +5 more
wiley +1 more source
Effects of adolescent exposure to methylmercury and d-amphetamine on reversal learning and an extradimensional shift in male mice. [PDF]
Boomhower SR, Newland MC.
europepmc +1 more source
Abstract Human binge eating disorder is characterized by recurrent episodes of excessive food consumption accompanied by loss of control and is strongly associated with alterations in reward processing and emotional regulation. Ayahuasca, a psychoactive botanical preparation traditionally used in Amazonian medicine, has been shown to modulate ...
Cristian Ferreira Corona +10 more
wiley +1 more source
ABSTRACT Background Ghana's response to substance use has long been dominated by criminalisation, yet limited research has examined how this policy environment shapes addiction treatment delivery. This study explored the perspectives of mental health nurses providing care to people who use drugs (PWUDs) using a socio‐ecological framework.
Evans F. Kyei +4 more
wiley +1 more source
ABSTRACT This study evaluated the psychometric properties and psychopathology correlates of the Patient‐Reported Outcome Measurement Information System (PROMIS) Pediatric Sleep Disturbance and Sleep‐related Impairment Self and Proxy Short Forms in early adolescents with and without attention‐deficit/hyperactivity disorder (ADHD).
Stephen P. Becker +2 more
wiley +1 more source

