Results 131 to 140 of about 16,318,448 (302)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

University Concert Band, April 6, 1990

open access: yes, 2016
Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, April 6, 1990, 8:00 p.m., the 356th concert of the School of Music’s 1989-1990 season.University Concert Band ; Miles Mortensen, conductor
Western Michigan University. Concert Band
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Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Band spectacular, November 14, 1975

open access: yes, 2016
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, November 14, 1975, program no. 66 of the Department of Music’s 1975-1976 season.University Symphonic Band, Carl Bjerregaard, conductor ; Andrew ...

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Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

University Symphonic Band, 1979, 02/18

open access: yes, 2018
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, February 18, 1979, program no. 159 of the Department of Music's 1978-1979 season.
Western Michigan University. Symphonic Band
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Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

University Symphonic Band, October 12, 1991 : a Sousa spectacular

open access: yes, 2016
Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, October 12, 1991, 8:00 p.m., the 46th concert of the School of Music’s 1991-1992 season.University Symphonic Band, Jeffrey Renshaw ...
Western Michigan University. Symphonic Band
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Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Band spectacular, December 3, 1978

open access: yes, 2018
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, November 17, 1978, program no. 67 of the Department of Music's 1978-1979 season.University Symphonic Band, Eddie Green, conductor (1st-3rd works) ;

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