Results 121 to 130 of about 19,818,191 (319)

University Symphonic Band, February 22, 1987

, 2014
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, February 22, 1987, 3:00 p.m., the 217th concert of the School of Music's 1986-1987 season.University Symphonic Band, Richard J.
Western Michigan University. Symphonic Band
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Pd‐Lined Strained Trimetallic Au‐Ag‐Pd Nanoprism for Enhanced Electrocatalytic Activity Towards Formic Acid Oxidation

Small Science
Formic acid oxidation (FAO) reaction is an important electrocatalytic reaction in low‐temperature proton exchange membrane fuel cells. Pd‐based material has a superior electrochemical activity towards FAO. The activity of Pd‐based bimetallic materials is
Sourav Mondal, Sandip Kumar De, Tanmay Ghosh, Subrata Mondal, Mihir Manna, Dulal Senapati   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

University Symphonic Band, October 9, 1994

, 2016
Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, October 9, 1994, 3:00 p.m., the 34th concert of the School of Music’s 1994-1995 season.University Symphonic Band, Robert Spradling ...
Western Michigan University. Symphonic Band
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Precise Pt-skin manipulation of strain and ligand effects for oxygen reduction

eScience
Nanostructured platinum (Pt)-skin alloys are promising electrocatalysts for oxygen reduction reaction (ORR) due to their tunable strain and ligand effects which essentially regulate the surface electronic structures. In addition to the chemical nature of
Yizhe Chen, Zeyu Jin, Jialin Sun, Shengli Chen, Jiujun Zhang, Shiming Zhang   +5 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Electronic descriptors for designing high-entropy alloy electrocatalysts by leveraging local chemical environments

Nature Communications
High-entropy alloys (HEAs) present a vast compositional space for fine-tuning electrocatalytic activities, leveraging millions of distinct active sites on the surface. However, the intricate local chemical environment poses challenges to the rational and
Guolin Cao, Sha Yang, Ji-Chang Ren, Wei Liu   +3 more
doaj   +1 more source