Results 141 to 150 of about 19,818,191 (319)

The Band spectacular, November 21, 1980

open access: yes, 2019
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan on November 21, 1980, 8:00 p.m., program no.

core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Graduate recital, band conducting. Druart, D. K., 1985

open access: yes, 2016
Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, April 11, 1985, the 289th concert of the School of Music's 1984-1985 season.University Concert Band, Donald K.
Druart, Donald K.
core   +2 more sources

University Concert Band, October 8, 1992

open access: yes, 2016
Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, October 8, 1992, 8:00 p.m., the 37th concert of the School of Music’s 1992-1993 season.University Concert Band, Stephen Grugin, conductor ...
Western Michigan University. Concert Band
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In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

The d-Band Center Theory in Heterogeneous Catalysis: A Comprehensive Guide for Catalyst Design

open access: yes
This article presents a detailed exploration of the d-band center theory, a crucial electronic descriptor that unifies principles in heterogeneous catalysis. Pioneered by Hammer and Nørskov, the theory posits that the mean energy of a transition metal's d-electron states, known as the d-band center (εd), dictates the strength of adsorbate binding on ...
openaire   +2 more sources

University Symphonic Band, December 7, 1975

open access: yes, 2016
Recorded during a live performance at Miller Auditorium, Western Michigan University, Kalamazoo, Michigan, December 7, 1975, program no. 94 of the Department of Music’s 1975-1976 season.University Symphonic Band, Carl Bjerregaard, conductor ; Jack Adams,
Western Michigan University. Symphonic Band
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Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

University Symphonic Band, October 12, 1991 : a Sousa spectacular

open access: yes, 2016
Recorded during a live performance at Dalton Center Recital Hall, Western Michigan University, Kalamazoo, Michigan, October 12, 1991, 8:00 p.m., the 46th concert of the School of Music’s 1991-1992 season.University Symphonic Band, Jeffrey Renshaw ...
Western Michigan University. Symphonic Band
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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