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D-dimer – a multifaceted molecule

Hormone Molecular Biology and Clinical Investigation
Abstract D-dimer, a universally unique marker for fibrin degradation, is generated through the enzymatic interplay of thrombin, factor XIIIa, and plasmin. The emergence of D-dimer-containing fibrin molecules occurs in both intravascular and extravascular spaces during pivotal physiological processes like haemostasis, thrombosis, and ...
Devika Tayal   +2 more
openaire   +2 more sources

Comparison of D-Dimer PLUS assay with NycoCard D-Dimer

Thrombosis and haemostasis, 2003
Measurement of D-dimer levels has gained widespread use in the diagnosis of various clinical situations that relate to thrombosis and fibrinolysis. Nowadays, different rapid and fully automated quantitative D-Dimer assays that can be performed on coagulation analyzers are commercially available.
Zadro, Renata, Coen Herak, Desiree
openaire   +2 more sources

D-Dimer in Venous Thromboembolism

New England Journal of Medicine, 2003
Venous thromboembolism is an important medical problem, with an estimated incidence in the United States of 100,000 to 300,000 cases per year. Of patients presenting with symptoms suggestive of deep venous thrombosis, only 30 percent actually have the disorder.
openaire   +2 more sources

D-dimer in Acute Aortic Dissection

Chest, 2003
Laboratory testing plays a minor role in the assessment of aortic dissection. Its main value is in the exclusion of other diseases. Following an incidental observation, we systematically investigated the relationship between elevated d-dimer levels and acute aortic dissection.We prospectively tested d-dimer levels in patients with suspected acute ...
Thomas, Weber   +6 more
openaire   +2 more sources

D-Dimer

2015
Bryan A. Cotton, Laura A. McElroy
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d-Dimer Assay

Annals of Emergency Medicine, 1998
openaire   +2 more sources

Age-adjusted D-dimer cutoffs to guide anticoagulation in COVID-19

Lancet, The, 2021
Marco Zuin   +2 more
exaly  

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