Results 111 to 120 of about 1,665,022 (280)
High speed single photon detection in the near-infrared
, 2007 InGaAs avalanche photodiodes (APDs) are convenient for single photon detection in the near-infrared (NIR) including the fibre communication bands (1.31/1.55 $\mu$m).
A. J. Shields +5 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
High-Efficiency Solar-Powered 3-D Printers for Sustainable Development
Machines, 2016 The release of the open source 3-D printer known as the RepRap (a self-Replicating Rapid prototyper) resulted in the potential for distributed manufacturing of products for significantly lower costs than conventional manufacturing.
Jephias Gwamuri +4 more
doaj +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The Role of Transport Infrastructures in determining Technical Efficiency in R&D activity of Italian regions. A double-bootstrapped DEA procedure [PDF]
, 2013 We measure technical efficiency in R&D of Italian regions with the aim of understanding whether the variation in transport infrastructure endowment across regions might be the cause of efficiency disparities.
Bergantino, Angela Stefania +2 more
core
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
D-optimal plans for variable selection in data bases [PDF]
This paper is based on an article of Pumplün et al. (2005a) that investigates the use of Design of Experiments in data bases in order to select variables that are relevant for classification in situations where a sufficient number of measurements of the ...
Schiffner, Julia, Weihs, Claus
core
Explicit finite element implementation of a shape memory alloy constitutive model and associated analyses [PDF]
, 2017 Shape memory alloys (SMA) represent an important class of smart metallic materials employed in various innovative applications thanks to their unique thermomechanical behavior.
Auricchio, F. +5 more
core
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source