Results 51 to 60 of about 1,724,790 (267)
Mine Field Preparation and Coal Mining in Western Donbas: Energy Security of Ukraine—A Case Study
Energies, 2022 Ukrainian electricity production sector is in a critical situation. It is necessary to increase the coal production to ensure the continuity of electricity production.
Oleksandr Haidai +7 more
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
ROLE OF VITAMIN D IN THE EFFICIENCY OF ANTIRESORPTIVE THERAPY
Современная ревматология, 2009 Vitamin D deficiency is one of the substantiated risk factors of osteoporosis. This vitamin is required to provide intestinal calcium absorption, bone metabolism regulation, and neuromuscular functions in the body.
N V Toroptsova
doaj +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
D-optimal and highly D-efficient designs with non-negatively correlated observations [PDF]
Kybernetika, 2016 In this paper we consider D-optimal and highly D-efficient chemical balance weighing designs. The errors are assumed to be equally non-negatively correlated and to have equal variances. Some necessary and sufficient conditions under which a design is D*-optimal design (regular D-optimal design) are proved. It is also shown that in many cases D*-optimal
Krystyna Katulska, Lukasz Smaga
openaire +1 more source
Drawing blanks and winning: Quantifying global catastrophic risk associated with human ingenuity
Sustainable FuturesIn his Vulnerable World Hypothesis Nick Bostrom recently compared invention to drawing balls out of a giant urn containing at least one black ball (i.e. an invention that would destroy civilization).
John-Oliver Engler, Jan Niklas Fischer
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Constructing D-Efficient Mixed-Level Foldover Designs Using Hadamard Matrices [PDF]
Technometrics, 2019 This paper introduces a new class of Hadamard matrix-based mixed-level foldover designs (MLFODs) and an algorithm which facilitates the construction of MLFODs.
Nam-Ky Nguyen +2 more
openaire +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source