Results 71 to 80 of about 1,724,790 (267)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Consequences on energy and water exchanges of airflow modifications in agrivoltaic systems

open access: yesEnergy Nexus
While solar radiation is essential for plant development, overexposure can exacerbate abiotic stresses, making soil water content the key driver affecting plant growth.
Joseph Vernier   +5 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

ANALYSIS OF EFFICIENCY OF R&D ACTIVITIES AMONG COUNTRIES WITH DEVELOPED AND DEVELOPING ECONOMIES INCLUDING REPUBLIC OF BELARUS WITH STOCHASTIC FRONTIER APPROACH

open access: yesНаука и техника, 2016
This study evaluates efficiency of R&D activities based on the stochastic frontier analysis across 69 counties with developed and developing economies.
I. V. Zhukovski, A. V. Gedranovich
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Deconstructing Markush: Improving the R&D Efficiency Using Library Selection in Early Drug Discovery. [PDF]

open access: yesPharmaceuticals (Basel), 2022
Manen-Freixa L   +3 more
europepmc   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Plant Friendly Input Design for Parameter Estimation in an Inertial System with Respect to D-Efficiency Constraints

open access: yesEntropy, 2014
System identification, in practice, is carried out by perturbing processes or plants under operation. That is why in many industrial applications a plant-friendly input signal would be preferred for system identification.
Wiktor Jakowluk
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Vitamin D Efficiency in Pregnancy: An Updated Viewpoint in Indian Scenario

open access: yesInternational Journal of Clinical Medicine, 2015
A decade ago identified as bone-building mineral improving calcium absorption, today new re-search opens potentials of Vitamin D in spectrum of diseases from diabetes, hypertension to cancer including special population like pregnancy & lactation.
Manish Maladkar   +2 more
openaire   +2 more sources

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