Results 71 to 80 of about 824,647 (268)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Effect of Geometric Parameters on the Behavior of Concrete-Filled Steel Tubular Frames

open access: yesTikrit Journal of Engineering Sciences
Concrete-filled steel tubular (CFST) technology offers numerous structural benefits, including outstanding strength, fire resistance, and a considerable capacity for energy absorption.
Ali K. Al-Asadi
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Probing new physics in $$B \rightarrow D \ell ^+ \ell ^-$$ B → D ℓ + ℓ - decays by using angular asymmetries

open access: yesEuropean Physical Journal C: Particles and Fields, 2017
We present a fully general, model-independent study of a few rare semileptonic B decays that get dominant contributions from W-annihilation and W-exchange diagrams, in particular $$B^0 \rightarrow \overline{D}{} ^0 \ell ^+\ell ^-$$ B 0 → D ¯ 0 ℓ + ℓ ...
C. S. Kim, Dibyakrupa Sahoo
doaj   +1 more source

Rational choice and framing devices: Argumentation and computer programming [PDF]

open access: yes, 2019
The argumentative discourse of computer programmers engaged in a collaborative programming task were analyzed as instances of ecologically valid reasoning behavior. Teams of expert programmers were brought into a laboratory setting to work cooperatively on a software maintenance task.
Coulson, Seana, Flor, Nick V .
openaire   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Quantization Noise Shaping on Arbitrary Frame Expansions

open access: yesEURASIP Journal on Advances in Signal Processing, 2006
Quantization noise shaping is commonly used in oversampled A/D and D/A converters with uniform sampling. This paper considers quantization noise shaping for arbitrary finite frame expansions based on generalizing the view of first-order classical ...
Boufounos Petros T, Oppenheim Alan V
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Parallel Transport Frame for Fiber Shape Sensing

open access: yesIEEE Photonics Journal, 2018
This paper reports a reconstruction method to determine a 3-D space curve from the distributed strain by using the parallel transport frame. Parallel transport frame can efficiently eliminate the singularities and discontinuous point which appear in ...
Jiwen Cui   +3 more
doaj   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

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