Results 131 to 140 of about 19,968,253 (257)
International Journal of Women's HealthQianjin Fang, Lin Sang, Shihua Du, Runqiu Wang, Haihong Wu, Lu Yang, Jie Yu Department of Obstetrics and Gynecology, The Second People’s Hospital of Hefei, Hefei Hospital Affiliated to Anhui Medical University, Hefei, Anhui Province, 230011, People’s ...
Fang Q +6 more
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Appel à com - Colloque "Culture et contre-culture" - Univ. Paris Ouest Nanterre
, 2011 COLLOQUE « CULTURE ET CONTRE-CULTURE : GENÈSES, PRATIQUES, CONCEPTUALISATIONS » Appel à communication Le Groupe d’analyse politique (GAP), le Centre d’études et de recherches sur l’espace germanophone (CEREG) et le Centre de recherches anglophones ...
gap
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Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
, 2011 Séminaire du Groupe d’Analyse Politique Paris Ouest Nanterre Responsables : Arnault SKORNICKI & Laurent BONELLI Calendrier des Séances 2010-2011 Le Mercredi,14h-16h — Bâtiment F – Salle des Actes (141) 17 novembre 2010 : « La mesure de l’assimilation ...
gap
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Estimating the output gap for the Maltese economy [PDF]
An attempt is made in this paper to arrive at an estimate of the output gap for the Maltese economy on a quarterly and annual basis. Two approaches are adopted, namely the Hodrick-Prescott filter and the aggregate production function method, with their ...
Grech, Aaron George
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Avl9 defines a family of DENN domain GTPase-activating proteins. [PDF]
J Cell BiolVignogna RC, Fromme JC.
europepmc +1 more source