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Thiosemicarbazones (TSC) have demonstrated promise as new chemotherapeutic agents against melanoma in both in vitro and In vivo studies. TSC are powerful metal coordinating agents, coordinating transition metal ions such as zinc, copper and iron in multiple oxidation states. It is this metal coordination that imparts the anticancer activity.
Rohina Alim +2 more
wiley +1 more source
Phytochemicals in Asthma Management: Mechanism, Translational Gap and Clinical Integration
The phytochemicals including flavonoids, alkaloids, terpenoids, and saponins modulate inflammatory, oxidative, and immune pathways in asthma. It highlights their mechanisms of action, translational challenges, advanced formulation strategies, and emerging clinical potential as adjunct therapies for precision‐based asthma management.
Pulak Majumder, Trisita Majumder
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Abstract Floral mimicry of decaying substrates of animal origin, such as carrion or faeces, is associated with unusual traits such as geoflory, deep maroon or yellow colouration, floral hairs and unpleasant odour, but the functional significance of these traits for attracting and manipulating pollinators has seldom been examined.
Adam Shuttleworth +3 more
wiley +1 more source
Snow Gum Dieback Enhances Trunk Monoterpene Emissions in the Australian Alps
Abstract Canopy decline is increasingly prevalent in high‐elevation snow gum (Eucalyptus pauciflora) forests across the Australian Alps. This phenomenon, known as snow gum dieback, is associated with infestations by the wood‐boring beetle, Phoracantha mastersi.
Marta Contreras‐Serrano +6 more
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Read the free Plain Language Summary for this article on the Journal blog. Abstract Plant‐ and microbial‐derived residues constitute the primary sources of soil organic carbon (SOC) in grassland ecosystems. However, their differential responses to chronic nitrogen (N) enrichment and the depth‐dependent mechanisms governing their accumulation remain ...
Xiaobo Yuan +19 more
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Schematic illustration of sous vide preparation of wild turkey meat and microbiological analysis of the meat. ABSTRACT In our study, we focused on the chemical composition of Rosmarinus officinalis essential oil (ROEO), its antimicrobial effects. Drawing from existing research, we further investigated the antimicrobial properties of ROEO under in vivo ...
Miroslava Kačániová +11 more
wiley +1 more source
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Nanodelivery systems for d-limonene; techniques and applications
Food Chemistry, 2022The d-limonene (DL), a bioactive ingredient in citrus peels, is a monoterpene, volatile, and aromatic flavor which has antioxidant, anti-inflammatory, and anti-cancer properties and many health-promoting effects. To protect DL against the harsh conditions during the processing and storage, its entrapment in biocompatible, biodegradable and safe ...
Sahar, Akhavan-Mahdavi +8 more
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Chemoprevention and Therapy of Cancer by d-Limonene
Critical Reviews™ in Oncogenesis, 1994The naturally occurring monoterpene d-limonene has chemopreventive and chemotherapeutic activity against many rodent solid tumor types. The chemopreventive activity of limonene during initiation can be attributed to the induction of phase I and phase II enzymes, with resulting carcinogen detoxification.
P L, Crowell, M N, Gould
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Influence of d-limonene on the transdermal penetration of felodipine
European Journal of Drug Metabolism and Pharmacokinetics, 1998Felodipine is a calcium antagonist, one of the dihydropyridines, with potential application in transdermal therapeutic systems (TTS). Earlier studies reported that the high lag time of this drug limited its potential development in a TTS. The present study analyzes the effect of d-limonene at concentrations of 0.5, 1, 5 and 10% on the transdermal ...
I, Diez +3 more
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Cyclocopolymerization of d-limonene with maleic anhydride
European Polymer Journal, 1981Abstract d -Limonene (Lim), a nonconjugated 1,5-diene, was copolymerized with maleic anhydride (MAn) in tetrahydrofuran with α,α′-azobisisobutyronitrile as initiator. The composition, spectral analyses, and other physical properties of the resulting copolymer and its hydrolysed product suggest that Lim readily undergoes an inter-intramolecular ...
T. Doiuchi, H. Yamaguchi, Y. Minoura
openaire +1 more source

