Results 91 to 100 of about 15,544,606 (299)
Effect of Collagen Cross-Linking on Alkali Burn-Induced Corneal Neovascularization in Rabbits
Journal of Ophthalmology, 2018 Objective. This study aims at investigating the effects and molecular mechanism of riboflavin-ultraviolet-A-induced cross-linking (corneal collagen cross-linking, CXL) on corneal neovascularization (CNV) in a rabbit alkali burn model. Methods. A total of
Xiaoying Xu, Taixiang Liu, Haixiang Li
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Roles of fibrin α- and γ-chain specific cross-linking by FXIIIa in fibrin structure and function [PDF]
, 2014 Factor XIII is responsible for the cross-linking of fibrin γ-chains in the early stages of clot formation, whilst α-chain cross-linking occurs at a slower rate.
Philippou, H +11 more
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Pre-release of Linking Lost Jazz Shrines data
, 2020 Pre-release of Linking Lost Jazz Shrines data at conclusion of Collections as Data, Cohort 1 grant.
Weeksville Heritage Center
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Similarity of wh-phrases and acceptability variation in wh-islands
Frontiers in Psychology, 2016 In wh-questions that form a syntactic dependency between the fronted wh-phrase and its thematic position, acceptability is severely degraded when the dependency crosses another wh-phrase.
Emily eAtkinson +3 more
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D-linking or set-restriction? ProcessingWhich-questions in Dutch
Language and Cognitive Processes, 2013 Research on Wh-questions suggests that Which questions are harder to process than Who questions (e.g., Who/Which athlete won the competition?). According to the Discourse (D)-linking Hypothesis, Which-questions differ from Who-questions in that Which questions need a link to a preceding discourse, while Who questions do not. However, this difference in
Donkers, Jantien +2 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
On linking numbers and Biot-Savart kernels
On a compact manifold, the solutions of the initial value problem for the heat equation with currential initial conditions are smooth families of forms for $t>0$.
Luciano Mari, Daniel Cibotaru
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