Results 91 to 100 of about 623,703 (301)

Vitamin D and Atopic Dermatitis in Childhood

open access: yesJournal of Immunology Research, 2015
Vitamin D features immunomodulatory effects on both the innate and adaptive immune systems, which may explain the growing evidence connecting vitamin D to allergic diseases.
Michelangelo Vestita   +4 more
doaj   +1 more source

The role of vitamin D in ovarian cancer: epidemiology, molecular mechanism and prevention

open access: yesJournal of Ovarian Research, 2018
Vitamin D is a fat-soluble prohormone best known for its role in maintaining calcium homeostasis. Large numbers of epidemiological studies have shown that vitamin D plays an important role in cancer prevention by regulating cellular proliferation and ...
Hui Guo   +4 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Long-term safety and efficacy follow-up of prophylactic higher fluence collagen cross-linking in high myopic laser-assisted in situ keratomileusis

open access: yesClinical Ophthalmology, 2012
Anastasios John KanellopoulosLaservision.gr Institute, Athens, Greece, and New York University Medical School, New York, NY, USABackground: The purpose of this study was to evaluate the safety and efficacy of ultraviolet A irradiation cross-linking on ...
Kanellopoulos AJ
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Effect of Collagen Cross-Linking on Alkali Burn-Induced Corneal Neovascularization in Rabbits

open access: yesJournal of Ophthalmology, 2018
Objective. This study aims at investigating the effects and molecular mechanism of riboflavin-ultraviolet-A-induced cross-linking (corneal collagen cross-linking, CXL) on corneal neovascularization (CNV) in a rabbit alkali burn model. Methods. A total of
Xiaoying Xu, Taixiang Liu, Haixiang Li
doaj   +1 more source

Specificity distinction [PDF]

open access: yes, 2013
This paper is concerned with semantic noun phrase typology, focusing on the question of how to draw fine-grained distinctions necessary for an accurate account of natural language phenomena.
Farkas, Donka F.
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

My topic is D-linked : aspects of wh-determination [PDF]

open access: yes, 2015
This work deals with so-called wh-determination. The notion of D-linking (Discourse-linking) is used to uncover and explain properties of constructions involving wh-determiners. The central claim is that there are two types of wh-determination: Token-whs and Kind-whs. These two forms of wh-determination trigger different syntactic effects.
openaire   +1 more source

D-linking or set-restriction? ProcessingWhich-questions in Dutch

open access: yesLanguage and Cognitive Processes, 2013
Research on Wh-questions suggests that Which questions are harder to process than Who questions (e.g., Who/Which athlete won the competition?). According to the Discourse (D)-linking Hypothesis, Which-questions differ from Who-questions in that Which questions need a link to a preceding discourse, while Who questions do not. However, this difference in
Donkers, Jantien   +2 more
openaire   +1 more source

Home - About - Disclaimer - Privacy