Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Efficacy and Safety of Corneal Collagen Cross-linking in Keratoconus; A One Year Follow-up
Journal of Islamic International Medical College, 2017 Objective: To evaluate the efficacy and safety of collagen cross linking in stabilizing the visual acuity and keratometric readings one year after the procedure. Study Design: A Case Series.
Aneeq Ullah Baig Mirza, Aamir Asrar, Bisma Ikram
doaj
Journal of Ophthalmology, 2016 Purpose. To assess the clinical and morphological outcomes of topography-guided accelerated corneal cross-linking. Design. Retrospective case series. Methods. 21 eyes of 20 patients with progressive keratoconus were enrolled.
Cosimo Mazzotta +5 more
doaj +1 more source
Assessing the role of the research in the transition to organic farming by using the Actor Network Theory: lessons from two case studies in France and Bulgaria [PDF]
, 2018 This paper explores the potential of Actor Network Theory (ANT) in understanding how the process of interaction and translation between human and non-human actors contribute to the development, adoption and diffusion of science-based innovations linked ...
Barjolle, Dominique +3 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Corneal Cross-Linking for Pediatric Keratoconus
DiagnosticsAim: The aim of this study was to evaluate corneal cross-linking (CXL) for keratoconus in pediatric patients. Materials and methods: After keratometric qualification according to the Amsler–Krumeich system, corneal collagen cross-linking was performed ...
Bogumiła Wójcik-Niklewska +2 more
doaj +1 more source
Программа обучения компании D-Link
, 2015 В статье рассмотрена программа обучения компании D-Link, способы и методы взаимодействия с учебными ...
openaire +2 more sources
Bringing the OpenMI to LIFE Progress Report No. 4 - 31st March 2008 – 30th September 2008 [PDF]
, 2008 The Water Framework Directive demands an integrated approach to water management. This requires the ability to predict how catchment processes will behave and interact in response to the activities of water managers and others.
Gregersen, Jan +5 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Information structure and the referential status of linguistic expression : workshop as part of the 23th annual meetings of the Deutsche Gesellschaft für Sprachwissenschaft in Leipzig, Leipzig, February 28 - March 2, 2001 [PDF]
, 2001 This volume comprises papers that were given at the workshop Information Structure and the Referential Status of Linguistic Expressions, which we organized during the Deutsche Gesellschaft für Sprachwissenschaft (DGfS) Conference in Leipzig in February ...
Heusinger, Klaus von, Schwabe, Kerstin
core