Results 141 to 150 of about 15,544,606 (299)
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Технологии D-LINK для агропромышленного комплекса
, 2019 Предметом, доклада является использование современных информационных технологий в агропромышленном комплексе. Доклад подготовлен в рамках соглашения о долговременном сотрудничестве в научной и образовательной деятельности в области информационных технологий между Белорусским Государственным аграрным университетом и Представительством ООО "D-link ...
openaire +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Clinical Ophthalmology, 2013 Bernhard Ralla, Christoph Holtmann, Gerd GeerlingDepartment of Ophthalmology, University of Düsseldorf, Düsseldorf, GermanyIt is with great interest that we read the publication by Kanellopoulos.1 In this the author shows in a group of ...
Ralla B, Holtmann C, Geerling G
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Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Linking number of grid models [PDF]
This paper studies the linking numbers of random links within the grid model. The linking number is treated as a random variable on the isotopy classes of 2-component links, with the paper exploring its asymptotic growth as the diagram size increases ...
Kotorii, Yuka, Barthel, Senja; id_orcid
core +1 more source
ReLink: Reliable Deep Learning for Microscopic Motion Tracking. [PDF]
Adv Sci (Weinh)Jiang Y +7 more
europepmc +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source