Results 161 to 170 of about 15,544,606 (299)

Transient Endothelial Damage Following FS-LASIK Combined With Corneal Cross-Linking Surgery: Case Report. [PDF]

Am J Case Rep
Wang L, Wang Y, Zhang X.
europepmc   +1 more source

Vitamin D Linked to Diabetes Mortality Risk [PDF]

Caring for the Ages, 2010
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Interplay between Thermal Denaturation and Dynamic Covalent Chemistry Generates High-Performance Recyclable Protein Plastics. [PDF]

ACS Macro Lett
Ma Y, Stellacci F.
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Rethinking Library Linking Breathing New Life into OpenURL

This issue of Library Technology Reports provides practicing librarians with real-world examples and strategies for improving resolver usability and functionality in their own institutions.Cover -- Title -- Copyright -- Contents -- Chapter 1-Introduction
Price, Jason., Trainor, Cindi.
core  

PAMOCAT: linking motion capturing and conversation analysis.

, 2012
Brüning B-A, Schnier C. PAMOCAT: linking motion capturing and conversation analysis. In: Morency L-P, Bohus D, Aghajan HK, et al., eds. ICMI. ACM Digital Library.
Morency, Louis-Philippe, Bohus, Dan, Association for Computing Machinery, Aghajan, Hamid K., Epps, Julien, Nijholt, Anton, Brüning, Bernhard-Andreas, Cassell, Justine, Schnier, Christian   +8 more
core  

Ambient light drives verteporfin-induced protein cross-linking during standard laboratory sample processing. [PDF]

PLoS One
Baroutis KG, Corrêa VSMC, Ntentakis D, Narimatsu T, Gragoudas ES, Miller JW, Young LH, Vavvas DG.   +7 more
europepmc   +1 more source