Results 231 to 240 of about 15,544,606 (299)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Extracellular matrix-inspired single-network gels with tunable tissue-like toughness and viscoelasticity for high-fidelity organ phantoms.

open access: yesJ Mater Chem B
Park J   +11 more
europepmc   +1 more source

Refractive Index Engineering for Human Corneal Tissue by Femtosecond Laser Two-Photon Cross-Linking. [PDF]

open access: yesJ Biophotonics
Qi P   +12 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

An Amphibious Bifunctional Probe for Protein Chemical Cross-Linking. [PDF]

open access: yesJ Am Chem Soc
Karpíšek M   +6 more
europepmc   +1 more source

The CYFIP2 Arg87Cys Mutation Reshapes the Interactome and Alters Stress Fiber-Associated Proteins. [PDF]

open access: yesACS Omega
V Biembengut Í   +7 more
europepmc   +1 more source

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