Results 131 to 140 of about 24,770,333 (307)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Microwave-assisted Preparation of Cross-linked Gelatin-Paracetamol Matrices: Optimization Using the D-optimal Design [PDF]
Turk J Pharm Sci, 2021 Kuang TK +5 more
europepmc +1 more source
Sequences Converging to $D$-Optimal Designs of Experiments
The Annals of Statistics, 1973 Fedorov (Theory of Optimal Experiments (1972)) gives a sequence of designs converging to a $D$-optimal design. Several modifications of that sequence are given to improve the speed of convergence. The analogous sequence for estimating some of the parameters is shown to converge to a $D$-optimal design, whether or not all the parameters are estimable ...
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Optimal Combinatorial Mechanism Design [PDF]
We consider an optimal mechanism design problem with several heterogeneous objects and interdependent values. We characterize ex post incentives using an appropriate monotonicity condition and reformulate the problem in such a way that the choice of an ...
Levent Ulku
core
Optimasi Formula Jamu Sinom Sediaan Celup Metode Mixture Design D-Optimal
Jurnal Teknologi PanganSinom merupakan jamu dengan bahan baku utama rimpang kunyit (Curcuma longa) dan daun asam jawa (Tamarindus indica L.) yang memiliki efek fungsional bagi kesehatan akibat senyawa bioaktif di dalamnya.
Diana Candra Wulandari +1 more
doaj +1 more source
Optimization for esterification of saturated palm fatty acid distillate by D-optimal design response surface methodology for biolubricant production. [PDF]
Turk J Chem, 2021 Jumaah MA, Salih N, Salimon J.
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
PharmacianaLung delivery can overcome the problems related to the effectiveness of tuberculosis treatment by increasing the drug concentration at the target site. Rifampicin as the first-line antibiotic for tuberculosis has low water solubility and is unstable in ...
I Komang Aan Adi Ricardo +1 more
doaj +1 more source
Second derivative synchronous fluorescence determination of avanafil in the presence of its acid-induced degradation product aided by powerful Lean Six Sigma tools augmented with D-optimal design. [PDF]
RSC Adv, 2021 Attia KAM +6 more
europepmc +1 more source