Results 111 to 120 of about 24,770,333 (307)

The D-optimal design of blocked and split-plot experiments with mixture components. [PDF]

open access: yes
So far, the optimal design of blocked and split-plot experiments involving mixture components has received scant attention. In this paper, an easy method to construct efficient blocked mixture experiments in the presence of fixed and/or random blocks is ...
Goos, Peter, Donev, AN
core  

D-OPTIMAL DESIGNS WITH ORDERED CATEGORICAL DATA [PDF]

open access: yes, 2017
Cumulative link models have been widely used for ordered categorical responses. Uniform allocation of experimental units is commonly used in practice, but often suffers from a lack of efficiency.
LP Tong (7937435)   +2 more
core   +3 more sources

Combined algorithm to compute D-optimal designs

open access: yesJournal of Computational and Applied Mathematics, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Raúl Martín Martín   +1 more
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Exact optimal designs for weighted least squares analysis with correlated errors [PDF]

open access: yes
In the common linear and quadratic regression model with an autoregressive error structure exact D-optimal designs for weighted least squares analysis are determined.
Kunert, Joachim, Dette, Holger
core  

Preparation of Spanlastics as A Promising Nanocarrier for Improving the Topical Delivery of Linezolid: I. Optimization, In Vitro Characterization, and Ex Vivo Evaluation

open access: yesBulletin of Pharmaceutical Sciences. Assiut University
Linezolid (LZD) is an effective oxazolidinone antibiotic against Gram-positive pathogens; however, its systemic side effects highlight the need for an effective topical delivery system.
Eman Samy   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Efficient D-optimal designs under multiplicative heteroscedasticity. [PDF]

open access: yes
In optimum design theory designs are constructed that maximize the information on the unknown parameters of the response function. The major part deals with designs optimal for response function estimation under the assumption of homoscedasticity.
Goos, Peter   +2 more
core  

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