Results 91 to 100 of about 24,770,333 (307)

On the number of support points of maximin and Bayesian D-optimal designs in nonlinear regression models [PDF]

open access: yes
We consider maximin and Bayesian D-optimal designs for nonlinear regression models. The maximin criterion requires the specification of a region for the nonlinear parameters in the model, while the Bayesian optimality criterion assumes that a prior ...
Dette, Holger, Braess, Dietrich
core  

D-Optimal designs for a multivariate regression model

open access: yesJournal of Multivariate Analysis, 1992
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Krafft, Olaf, Schaefer, Martin
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

An Advance Distributed Control Design for Wide-Area Power System Stability [PDF]

open access: yes, 2013
The development of control of a power system that supply electricity is a major concern in the world. Some trends have led to power systems becoming overstated including the rapid growth in the demand for electrical power, the increasing penetration of ...
Atawi, Ibrahem E
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Design of a new prebiotic beef snack formulation by D-optimal mixture design

open access: yesJournal of Agriculture and Food Research
This study optimized a prebiotic beef snack formulation using inulin, wheat flour, and corn flour at a 12 % ratio via the D-optimal mixture design. Samples were analyzed for physicochemical and sensory properties.
Hassan Dadkhah   +8 more
doaj   +1 more source

Simulations on the Combinatorial Structure of D-Optimal Designs [PDF]

open access: yes, 2018
In this work we present the results of several simulations on main-effect factorial designs. The goal of such simulations is to investigate the connections between the $D$-optimality of a design and its geometrical structure. By means of a combinatorial object, namely the circuit basis of the design matrix, we show that it is possible to define a ...
Roberto Fontana, Fabio Rapallo
openaire   +5 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Introducing Experience Goals into Packaging Design [PDF]

open access: yes, 2016
Consumer experiences are an increasingly important driving force for commerce, affecting also packaging design. Yet, experience design for packages is rarely studied.
Roto, Virpi   +3 more
core   +1 more source

Optimization, physical-chemical evaluation and healing activity of chitosan ointment [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2019
Context: Chitosan has received attention as a functional, sustainably renewable, nontoxic and biodegradable biopolymer for pharmaceutical applications such as healing agent.
Dania Pérez   +5 more
doaj  

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