Results 61 to 70 of about 231,256 (313)

Bayesian D-Optimal Choice Designs for Mixtures [PDF]

Journal of the Royal Statistical Society Series C: Applied Statistics, 2014
SummaryConsumer products and services can often be described as mixtures of ingredients. Examples are the mixture of ingredients in a cocktail and the mixture of different components of travel time (e.g. in-vehicle and out-of-vehicle travel time) in a transportation setting.
Ruseckaite, Aiste, Goos, Peter, Fok, Dennis   +2 more
openaire   +5 more sources

REGULAR D-OPTIMAL SPRING BALANCE WEIGHING DESIGNS: CONSTRUCTION

Acta Universitatis Lodziensis. Folia Oeconomica, 2014
Spring balance weighing design there is the model of experiment in that the result of experiment we can present as linear combination of unknown measurements of objects with factors of this combination equal to zero or one.
Bronisław Ceranka
doaj  

Optimal Designs for Multi-Group Linear Models with Measurement Errors

Mathematics
Multi-group linear models with measurement errors are frequently employed in situations where covariates cannot be precisely measured, thereby compromising the validity of between-group comparisons.
Min-Jue Zhang, Min-Qian Liu, Xue-Ping Chen   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Exact D-optimal designs of experiments for linear multiple regression with heteroscedastic observations

Журнал Белорусского государственного университета: Математика, информатика, 2018
In article the problem of construction of exact D-optimal designs of experiments for linear multiple regression in a case when variance of errors of observations depend on a point in which is made is investigated. The class functions describing change of
Valery P. Kirlitsa
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Optimal designs for indirect regression [PDF]

, 2004
In many real life applications, it is impossible to observe the feature of interest directly. For example, scientists in Materials Science may be interested in detecting cracks inside objects, not visible from the outside. Similarly, non-invasive medical
Edmund Jones, G. Vitale, Osses Alvarado, Axel, Nicolai Bissantz, Vitale, Guido, Cumsille, Patricio, Takahashi, Takéo, Hajo Holzmann, Chern, I-Liang, Conca, Carlos, Preziosi, Luigi, Kavian, O., L. Preziosi, Zuo, D., Langer, Matthias, Censor, Yair, Mueller, J. L., Ambrosi, Davide Carlo, Malik, Muslim, Schwindt, Erica L., Anthony Dubois, Herrera, C. N. L., Bissantz, Nicolai, Hamilton, S. J., Horng-Shing Lu, Henry, Pierro, Álvaro Rodolfo De, Schwindt, Erica, Rosier, Lionel, Helou Neto, Elias Salomão, Muslim Malik, Marc Saillard, Cheney, Margaret, Jiang, Ming, Kawano, Alexandre, Kamal Belkebir, Dette, Holger, Alvarez, Catalina, Von Herrmann, A., Holger Dette, Monard, F., Margaret Cheney, Holzmann, Hajo, Courdurier Bettancourt, Matías, Borden, Brett, Friz, L., Pandolfi, Luciano, Chen, Tai-Been, Romero, F., Brett Borden, Stefanie Biedermann, Conca Rosende, Carlos, Munnier, Alexandre, Ortega Palma, Jaime, Jones, Edmund, Woracek, Harald, Carlos Conca, Biedermann, Stefanie, Hamilton, Sarah J., Alexandre Munnier   +58 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

D-optimal and highly D-efficient designs with non-negatively correlated observations [PDF]

, 2016
summary:In this paper we consider D-optimal and highly D-efficient chemical balance weighing designs. The errors are assumed to be equally non-negatively correlated and to have equal variances.
Katulska, Krystyna, Smaga, Łukasz
core   +1 more source