Results 141 to 150 of about 18,707,175 (333)
Robustness properties of minimally‐supported Bayesian D‐optimal designs for heteroscedastic models [PDF]
, 2001 Holger Dette, Dale Song, Weng Kee Wong
openalex +1 more source
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
ADMM for 0/1 D-Opt and MESP relaxations [PDF]
arXivThe 0/1 D-optimality problem and the Maximum-Entropy Sampling problem are two well-known NP-hard discrete maximization problems in experimental design. Algorithms for exact optimization (of moderate-sized instances) are based on branch-and-bound. The best upper-bounding methods are based on convex relaxation.
arxiv
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Interplay of integrins and selectins in metastasis
Molecular Oncology, EarlyView.Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva +2 more
wiley +1 more source
The Optimal Design of Preform in 3-D Forging by using Electric Field Theory [PDF]
, 2002 openalex +1 more source
New parametric identification method for a preference model [PDF]
arXivThis article presents a contribution to multi-criteria decision support intended for industrial decision-makers in order to determine the best compromise between design criteria when working on risky or innovative products. In (RENAUD et al. 2008) we used the OWA operator (Ordered Weighted Average), a well-known multi-criteria analysis technique ...
arxiv
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Optimum level of spray-dried porcine plasma for early-weaned (10.5 d of age) starter pigs
, 1993 K Q Owen +4 more
openalex +2 more sources
Preoperative Analysis of Optimal Imaging Orientation in Fluoroscopy for Voxel-Based 2-D/3-D Registration [PDF]
, 2002 Yoshikazu Nakajima +8 more
openalex +1 more source