Results 201 to 210 of about 10,339,939 (316)

Pareto optimality reveals an atlas of cellular archetypes. [PDF]

Proc Natl Acad Sci U S A
Crowley G, Alon U, Quake SR.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

A computational mechanism linking momentary craving and decision-making in alcohol drinkers and cannabis users. [PDF]

Nat Ment Health
Kulkarni KR, Berner LA, Rhoads SA, Fiore VG, Schiller D, Gu X.   +5 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Neuromotor and Cognitive Outcomes of Preterm Infants at 3 Months of Corrected Age in a Northeastern Region of Brazil: Longitudinal Feasibility Study. [PDF]

JMIR Form Res
de Figueiredo Silva N, Lima-Alvarez CD, Dusing S, Pereira SA.   +3 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Distributed Nonparametric Regression with Heterogeneity Through Prediction-Based Aggregation. [PDF]

J Comput Graph Stat
Chen Z, Li R, Xu Y.
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Ferritin Reference Curves and Optimal Curves in Preadolescent Children.

JAMA Netw Open
Bijelic V, Momoli F, Liebman M, Potter BK, Borkhoff CM, Birken CS, Maguire JL, Parkin PC, Hamid JS.   +8 more
europepmc   +1 more source

Bayesian Sample Size Calculations for External Validation Studies of Risk Prediction Models. [PDF]

Stat Med
Sadatsafavi M, Gustafson P, Setayeshgar S, Wynants L, D Riley R.   +4 more
europepmc   +1 more source