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Computing Optimal Designs of multiresponse Experiments reduces to Second-Order Cone Programming [PDF]

open access: yes, 2010
Elfving's Theorem is a major result in the theory of optimal experimental design, which gives a geometrical characterization of $c-$optimality. In this paper, we extend this theorem to the case of multiresponse experiments, and we show that when the ...
Sagnol, Guillaume
core   +1 more source

Notes on D-optimal designs

open access: yesLinear Algebra and its Applications, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Neubauer, Michael G.   +2 more
openaire   +2 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Optimizing the intrinsic parallel diffusivity in NODDI: An extensive empirical evaluation.

open access: yesPLoS ONE, 2019
PurposeNODDI is widely used in parameterizing microstructural brain properties. The model includes three signal compartments: intracellular, extracellular, and free water. The neurite compartment intrinsic parallel diffusivity (d∥) is set to 1.7 μm2⋅ms-1,
Jose M Guerrero   +8 more
doaj   +1 more source

Highly D‑efficient Weighing Design and Its Construction

open access: yesActa Universitatis Lodziensis. Folia Oeconomica, 2017
In this paper, some aspects of design optimality on the basis of spring balance weighing designs are considered. The properties of D‑optimal and D‑efficiency designs are studied.
Bronisław Ceranka, Małgorzata Graczyk
doaj   +1 more source

Elfving's Theorem for $D$-Optimality

open access: yesThe Annals of Statistics, 1993
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

About Some Properties and Constructions of Experimental Designs

open access: yesActa Universitatis Lodziensis. Folia Oeconomica, 2016
In this paper, we consider the problems related to the determining plan of the experiment performed according to the model of the chemical balance weighing design under additional assumption that the experimental errors are equally negatively correlated.
Bronisław Ceranka, Małgorzata Graczyk
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Model accuracy and data heterogeneity shape uncertainty quantification in machine learning interatomic potentials

open access: yesMachine Learning: Science and Technology
Machine learning interatomic potentials (MLIPs) enable accurate atomistic modeling, but reliable uncertainty quantification (UQ) remains elusive. In this study, we investigate two UQ strategies, ensemble learning and D-optimality, within the atomic ...
Fei Shuang   +4 more
doaj   +1 more source

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