Results 61 to 70 of about 10,339,939 (316)

Differential-integral Euler–Lagrange equations [PDF]

Iranian Journal of Numerical Analysis and Optimization
We study the calculus of variations problem in the presence of a system of differential-integral (D-I) equations. In order to identify the necessary optimality conditions for this problem, we derive the so-called D-I Euler–Lagrange equations.
Mohammedd Shehata
doaj   +1 more source

Optimization Design of Step Stress Accelerated Degradation Test for Motorized Spindle Based on D_s-Optimality

Applied Sciences, 2021
In the accelerated degradation test (ADT) of motorized spindles, it is necessary to apply a variety of stresses to simulate real working conditions. However, the traditional accelerated test scheme optimization method does not consider the weight of ...
Hongxun Zhao, Zhaojun Yang, Chuanhai Chen, Hailong Tian, Xiaoxu Li, Shizheng Li   +5 more
doaj   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Notes on D-optimal designs

Linear Algebra and its Applications, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Neubauer, Michael G., Watkins, William, Zeitlin, Joel   +2 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Optimal design for additive partially nonlinear models [PDF]

, 2010
We develop optimal design theory for additive partially nonlinear regression models, showing that Bayesian and standardized maximin D-optimal designs can be found as the products of the corresponding optimal designs in one dimension.
D. C. Woods, Dette, H., Woods, D. C., Dette, Holger, H. Dette, Woods, David C., Biedermann, S., Woods, D.C., S. Biedermann, Biedermann, Stefanie   +9 more
core   +1 more source

Duality under novel generalizations of the D-type-I functions for multiple objective nonlinear programming problems

Scientific African
In this paper, we provide novel generalizations of the D-type-I functions by relaxing the D-Preinvexity functions using the mean-valued theorem. Under these new generalizations of the D-Preinvexity type-I functions, we also study the optimality solutions
Mohamed Abd El-Hady Kassem, Laxmi Rathour   +1 more
doaj   +1 more source

Optimal Designs For the Restricted Maximum Likelihood Estimators in a Random Split-Plot Model

Lithuanian Journal of Statistics, 2017
The design effect for the restricted maximum likelihood estimators of variance components in acompletely randomized split-plot model is studied. The model was used to represent the response generated froman experimental scenario where the whole-plot and
Oluwole Nuga, G. N. Amahia, Fatai Salami
doaj   +1 more source