Results 81 to 90 of about 10,339,939 (316)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
On optimality in intergenerational risk sharing [PDF]
This paper defines and studies optimality in a dynamic stochastic economy with finitely lived agents, and investigates the optimality properties of an equilibrium with or without sequentially complete markets.
Gabrielle Demange
core
In this paper, we propose to start addressing the issues outlined above from the perspective of Optimality Theory (OT, Prince and Smolensky, 1993) and test the hypothesis that different patterns of extractability across languages result from different ...
Raymond, William +4 more
core +1 more source
English stress preservation and Stratal Optimality Theory [PDF]
Since Chomsky & Halle (1968), English stress preservation has been important in generative discussions of morphophonological interaction. This thesis carries out empirical investigations into English stress preservation, and uses their results to argue ...
Collie, Sarah
core +1 more source
A Highly D‑efficient Spring Balance Weighing Design for an Even Number of Objects
The problem of determining unknown measurements of objects in the model of spring balance weighing designs is presented. These designs are considered under the assumption that experimental errors are uncorrelated and that they have the same variances ...
Małgorzata Graczyk, Bronisław Ceranka
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
D-optimal designs via a cocktail algorithm [PDF]
A number of changes after accounting for the referees' comments including new examples in Section 4 and more detailed explanations ...
openaire +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The object of the present work is the analysis of the convergence behaviour of a learning algorithm for grammars belonging to a special version -- the maximum entropy version -- of stochastic Optimality Theory.
Fischer, Markus
core +1 more source

