Results 91 to 100 of about 13,560,800 (313)
On optimality in intergenerational risk sharing [PDF]
This paper defines and studies optimality in a dynamic stochastic economy with finitely lived agents, and investigates the optimality properties of an equilibrium with or without sequentially complete markets.
Gabrielle Demange
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
On the Equivalence of Optimality Design Criteria for the Placebo-Treatment Problem [PDF]
We consider a class of optimality criteria and show that each crite- rion has its unique and equivalent dual within the class. This property can be used to find a variety of optimal designs, including a class of compound optimal designs and their ...
Zhu, Wei, Dette, Holger, Wong, Weng Kee
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Degraded acceptability and markedness in syntax, and the stochastic interpretation of optimality theory [PDF]
, 2004 The argument that I tried to elaborate on in this paper is that the conceptual problem behind the traditional competence/performance distinction does not go away, even if we abandon its original Chomskyan formulation. It returns as the question about the
Vogel, Ralf
core +1 more source
On the Smith normal form of D-optimal designs
Linear Algebra and its Applications, 1996 A \((2v\times 2v)\)-matrix with entries from \(\{-1, 1\}\) is called a \(D\)-optimal design of order \(2v\) if it has maximum determinant in the class of all matrices of this type. The authors study the Smith normal form (SNF) of designs in order to have sufficient conditions that two designs are not permutation-equivalent.
Koukouvinos, Christos +2 more
openaire +3 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Bayesian sequential D-D optimal model-robust designs. [PDF]
Alphabetic optimal design theory assumes that the model for which the optimal design is derived is usually known. However in real-life applications, this assumption may not be credible, as models are rarely known in advance.
Ruggoo, A, Vandebroek, Martina
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An Optimality Theoretic Approach to Navajo Prefixal Syllables
, 1998 An Optimality Theoretic Approach to Navajo Prefixal Syllables Amy V. Fountain University of Arizona Navajo is a Southern Athapaskan language spoken by approximately 160,000 people in Arizona and New Mexico.
Fountain, Amy Velita
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Hodges-Lehmann Optimality for Testing Moment [PDF]
This paper studies the Hodges and Lehmann (1956) optimality of tests in a general setup. The tests are compared by the exponential rates of growth to one of the power functions evaluated at a fixed alternative while keeping the asymptotic sizes bounded ...
Ivan Canay, Taisuke Otsu
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