Results 101 to 110 of about 10,339,939 (316)

Some optimality principles of sentence pronunciation

open access: yes, 1998
This is a compilation of handouts from 5 classes, Fall 1994, MIT, in which the proposal is advanced that the output of syntax feeds a system that determines how syntactic units are pronounced -- for example, optional and obligatory patterns of deletion ...

core  

Subsampling Algorithms for Irregularly Spaced Autoregressive Models

open access: yesAlgorithms
With the exponential growth of data across diverse fields, applying conventional statistical methods directly to large-scale datasets has become computationally infeasible.
Jiaqi Liu   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

D-Optimality and DL-optimality criteria for incomplete block designs

open access: yes, 2010
The adequacy of an experimental design can be determined from the information matrix. The D-optimality criterion is based on the determinant of the information matrix M(ξ) (ξ is any design measure) of a design, that is it maximizes the determinant ...
Madukaife, M.S, Oladugba, A.V
core   +1 more source

On the Smith normal form of D-optimal designs

open access: yesLinear Algebra and its Applications, 1996
A \((2v\times 2v)\)-matrix with entries from \(\{-1, 1\}\) is called a \(D\)-optimal design of order \(2v\) if it has maximum determinant in the class of all matrices of this type. The authors study the Smith normal form (SNF) of designs in order to have sufficient conditions that two designs are not permutation-equivalent.
Koukouvinos, Christos   +2 more
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Typology of Rounding Harmony: An Optimality Theoretic Approach

open access: yes, 1995
This thesis explores the typology of rounding harmony within the framework of optimality theory. A systematic survey of the range of attested rounding harmony phenomena is presented and an analysis of this typology is proposed which invokes constraints ...
Kaun, Abigail Rhoades
core   +1 more source

Multicriteria Optimization Model to Generate on‐DEM Optimal Channel Networks

open access: yesWater Resources Research, 2018
The theory of optimal channel networks (OCNs) explains the existence of self‐similarities in river networks by multiple optimality principles, namely, (i) the minimum energy expenditure in any link, (ii) the equal energy expenditure per unit area of ...
Simone Bizzi   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Evaluating the complexity of optimality theory

open access: yes, 2009
Idsardi (2006) claims that Optimality Theory (OT; Prince and Smolensky (1993/2004) is "in general computationally intractable" on the basis of a proof adapted from Eisner (1997). We take issue with this conclusion on two grounds.

core  

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