Results 111 to 120 of about 10,339,939 (316)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Autosegmental spreading in optimality theory
, 2011 This paper is a shorter version of ROA-1009 'Harmony in harmonic serialism'. Some material is omitted, but the overall presentation is probably clearer.The publisher of the book in which this excerpt appears does not permit the archiving of this or any ...
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Optimality Theory: Constraint Interaction in Generative Grammar
, 2002 This work develops a conception of grammar in which optimality with respect to a set of constraints defines well-formedness. The argument begins with a brief assessment of the promise of optimization-based approaches, focusing on issues of explanation ...
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Measuring Tax Efficiency: A Tax Optimality Index [PDF]
This paper introduces an index of tax optimality that measures the distance of a current tax structure from the optimal tax structure in the presence of public goods.
Pascalis Raimondos-Møller +1 more
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Morphologically Governed Accent in Optimality Theory
, 1999 This dissertation examines the influence of morphological factors on stress and pitch accent. Two basic types are recognized. In root-controlled accent, inherent accent in a root overrides inherent affix accent; as a result, affixal accent is only ...
Alderete, John D.
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Non-computable functions in Optimality Theory
, 1999 Is Optimality Theory a constraining theory? A formal analysis shows that it is, if two auxiliary assumptions are made: (1) that only markedness and faithfulness constraints are allowed, and (2) that input and output representations are made from the same
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D-Invexity and optimality conditions
, 1991 In this paper, a generalization of convexity, called d-invexity, is introduced. Substituting d-invex for convex, we get some optimality conditions for nondifferentiable multiobjective programming.
Ye, Y.L
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The Interaction of Yer Deletion and Nasal Assimilation in Optimality Theory1 [PDF]
, 2015 The problem of opacity presents a challenge for generative phonology. This paper examines the process of Nasal Assimilation in Polish rendered opaque by the process of Vowel Deletion in Optimality Theory (Prince & Smolensky, 1993), which currently is a ...
Iwan, Karolina
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