Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Mental Scene and Memory Construction and the Hippocampus. [PDF]
Rolls ET.
europepmc +1 more source
In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller +3 more
wiley +1 more source
Short-term changes in behavioral determinants following a theory-based workplace musculoskeletal health program among automobile manufacturing workers: a two-cluster program evaluation. [PDF]
Cho JY, Kim G.
europepmc +1 more source
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page +4 more
wiley +1 more source
Measurement properties of a patient-reported outcome scale for peptic ulcer: a validation study using classical test theory and generalizability theory. [PDF]
Xu F +8 more
europepmc +1 more source
Pathogenesis and therapeutic strategies for irritable bowel syndrome: an integrated perspective from dynamic balance theory of Chinese medicine. [PDF]
Liu N, Huang Y, Wang Y, Qiao H.
europepmc +1 more source
Comparative study of femtosecond laser ablation of glass using ultrathin gold and nickel films as sensitizers. [PDF]
Dave A +4 more
europepmc +1 more source

