Results 161 to 170 of about 15,113,067 (348)

D. Trump’s MAGAnomics: two years of presidency [PDF]

open access: yesRussia and America in the 21st Century, 2019
openaire   +1 more source

Intracellular retention of mutant retinoschisin is the pathological mechanism underlying X-linked retinoschisis.

open access: yesHuman Molecular Genetics, 2002
Tao Wang   +5 more
semanticscholar   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Molecular pathology of X linked retinoschisis: mutations interfere with retinoschisin secretion and oligomerisation

open access: yesBritish Journal of Ophthalmology, 2005
T. Wang   +5 more
semanticscholar   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Social Identity and the Mexican Community

open access: yes, 2019
The election of President Trump can be shown to negatively impact the Mexican community through social identity theory. Since his election, President Trump has passed policies controlling immigration and uses harmful language to describe Mexicans, such ...
Gallardo Vidaurre, Manuel Alexander   +1 more
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