Results 171 to 180 of about 232,754 (286)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Globalization and health in an emerging new world order. [PDF]

Global Health
Labonté R, Gleeson D, Joarder T, Paremoer L, Storeng K, van de Pas R.   +5 more
europepmc   +1 more source

President D. Trump’s tax reform and its economic consequences [PDF]

Russia and America in the 21st Century, 2019
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Concomitant Enhancement of the Reorientational Dynamics of the BH₄ ^- Anions and Mg²⁺ Ionic Conductivity in Mg(BH₄)₂·NH₃ upon Ligand Incorporation. [PDF]

J Phys Chem C Nanomater Interfaces
Grinderslev JB, Amdisen MB, Larsen SR, Trump BA, Karlsson M, Zhou W, Udovic TJ, Cheng Y, Tominaga T, Jensen TR, Andersson MS.   +10 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Behind political affiliation: How moral values, identity politics, and party loyalty have affected COVID-19 vaccination. [PDF]

PLoS One
Fortunato P, Lombini A.
europepmc   +1 more source

US Economic Recovery in 2017–2019: D. Trump’s Factor [PDF]

Russia and America in the 21st Century, 2019
openaire   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Information from social ties predicts conspiracy beliefs: Evidence from the attempted assassination of Donald Trump. [PDF]

PNAS Nexus
Ognyanova K, Druckman JN, Schulman J, Baum MA, Perlis RH, Lazer D.   +5 more
europepmc   +1 more source