Results 81 to 90 of about 232,754 (286)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

D. Trump's Policy in Latin America: Outcomes and Prospects

open access: yesPerspectives and prospects. E-journal, 2020
The Trump administration's policy south of the Rio Grande has revived the use of force in the spirit of infamous Monroe Doctrine and big stick diplomacy. As a result, an atmosphere of unpredictability has arisen between the United States and Latin America, and current trends in inter-American relations could be analyzed from the perspective of ...
openaire   +1 more source

Separate and Legally Unequal – How The Demonization of Immigrants Affects United States Policy [PDF]

open access: yes, 2012
Samverkan blir allt vanligare som organisatorisk lösning på situationer där ansvarsområden är vaga eller skär över organisationsgränser. Inom området vård och omsorg om äldre korsar ansvaret gränser både avseende huvudmän och yrkesgrupper och satsningar ...
Hernández, Laura A.
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

USA and leftist regimes in Latin America: D. Trump administration approach

open access: yesИбероамериканские тетради, 2019
The article is devoted to the policy of the Donald Trump administration toward the leftist regimes of Latin America: Venezuela, Cuba and Nicaragua.Washington’s strategy and tactics are examined, the reasons for its diplomacy are determined.The efficiency
D. M. Rozental
doaj   +1 more source

Trump and Sanders Supporters Differ Sharply on Key Scientific Fact [PDF]

open access: yes, 2015
In this fact sheet, author Lawrence C. Hamilton reports the results of a recent WMUR/CNN poll by the UNH Survey Center asking more than 700 New Hampshire residents whether they would vote for Donald Trump or Bernie Sanders if the 2016 presidential ...
Hamilton, Lawrence C.
core   +1 more source

Responding to Hate: How National and Local Incidents Sparked Action at the UNLV University Libraries

open access: yes, 2020
Purpose: The purpose of this paper is to describe how an academic library at one of the most diverse universities in the country responded to the 2016 election through the newly formed Inclusion and Equity Committee and through student outreach.
Cheng, James   +2 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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