Results 131 to 140 of about 147,924 (242)

Pharmacological Inhibition of APT2 by Solasonine Promotes Ferroptosis Through Palmitoylation Modulation in Gallbladder Cancer

Phytotherapy Research, EarlyView.
Schematic illustration of SS‐induced ferroptosis through targeting APT2‐mediated STAT3 palmitoylation in GBC cells. ABSTRACT Gallbladder cancer (GBC), the most prevalent and lethal biliary tract malignancy, lacks effective therapeutic strategies. Solasonine (SS), a bioactive steroidal alkaloid derived from Solanum nigrum L, exhibits antitumor activity ...
Liu‐qing Shi, Jing‐wei Zhao, Jia‐yun Zhu, Cheng Zhao, Zi‐yi Yang, Li‐jia Pan, Ben Ma, Zheng‐yu Chen, Zi‐ying Wang, Chun‐jie Li, Shi‐lei Liu, Jia‐wei Mei, Ping Dong   +12 more
wiley   +1 more source

Diagnóstico sobre a gestão da qualidade em empresas de construção civil de pequeno e médio porte no Brasil [PDF]

, 2016
Trabalho de conclusão de curso (graduação)—Universidade de Brasília, Faculdade de Tecnologia, Departamento de Engenharia de Produção, 2016.O presente estudo tem como objetivo analisar, por meio de levantamento bibliográfico, como a gestão da qualidade ...
Santos, Fernando Amadeu Machado
core  

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

Mesoscale and microphysical processes leading to extreme hourly rainfall prior to the merger of two mesoscale convective systems in Central China

Quarterly Journal of the Royal Meteorological Society, EarlyView.
Short‐term extreme rainfall can be produced by the variation of low‐level warm moist airflow during mesoscale convective systems (MCSs) approaching another. The cold outflow of the rapidly moving MCS intensifies the warm moist airflow in front, enhancing the convergence and ascending motion in the quasi‐stationary MCS.
Xiaoyu Gao, Yali Luo, Jinfang Yin, Chong Wu   +3 more
wiley   +1 more source

Problems of territorial integration and formation of ethnic groups in the USSR in the late 1920s – early 1930s (by the example of Mordovian Autonomy establishment)

Известия высших учебных заведений. Поволжский регион: Гуманитарные науки
Background. The research into regional identity formation is required by searching for effective practices to ensure sustainable regional development in the face of globalization challenges. The purpose of the study is a comprehensive review of Mordovian
O.A. Sukhova, O.A. Filenkova
doaj   +1 more source

A UAV‐based deep learning pipeline for intertidal macrobenthos monitoring: Behavioral and age classification in Tachypleus tridentatus

Remote Sensing in Ecology and Conservation, EarlyView.
The endangered tri‐spine horseshoe crab (Tachypleus tridentatus), a “living fossil” crucial to coastal ecology and biomedical research, is experiencing severe population declines. Effective conservation requires efficient monitoring, which traditional methods cannot deliver at scale. We develop an integrated UAV deep learning framework tailored to this
Xiaohai Chen, Yuyuan Bao, Ziwei Ying, Mujiao Xie, Ting Li, Jixing Zou, Jun Shi, Xiaoyong Xie   +7 more
wiley   +1 more source

Clubs and museums of Vladimir Vysotsky as a poet image-building mechanism in the socio-cultural discourse of Russia

Известия высших учебных заведений. Поволжский регион: Гуманитарные науки
Background. The active study of the processes of historical memory formation in science as an indicator of social and cultural transformations of society necessitates deter-mining the place of Vladimir Vysotsky work in the historical and cultural ...
S.V. Nikolaev
doaj   +1 more source

Who gets redeployed? Inventor characteristics and resource redeployment decisions

Strategic Management Journal, EarlyView.
Abstract Research Summary While the literature highlights the benefits of internally redeploying resources, there is less empirical guidance on which resources are most likely to be redeployed. We examine the relationship between inventor characteristics and redeployment decisions, motivated by the tension between costs and benefits of keeping a ...
Kyungsoo Kim, Isin Guler, Samina Karim
wiley   +1 more source

The regional branch of the Imperial Orthodox Palestine Society in Penza region at the beginning of the 21st century (2018–2023): structure, main directions and content of work

Известия высших учебных заведений. Поволжский регион: Гуманитарные науки
Background. The history of the regional chapters of the Imperial Orthodox Pales-tine Society (IOPS) begins almost immediately, only a few years later, after the emergence of the society itself (1882). As spokesmen for the ideas of society in the regions,
A.B. Shigurova
doaj   +1 more source

When do firms learn by hiring? How complexity moderates the value of new knowledge

Strategic Management Journal, EarlyView.
Abstract Research Summary Organizations often hire employees hoping to acquire new knowledge. While the literature has paid considerable attention to the role of the characteristics of the source of knowledge, the recipient firm, and the knowledge being transferred, it has largely overlooked those of the knowledge being replaced.
Dong Nghi Pham, Luis A. Rios, Maciej Workiewicz   +2 more
wiley   +1 more source