Results 41 to 50 of about 5,831 (180)

Point-of-Care Electrochemical Diagnostic Developments for Multidrug-Resistant Bacteria: Role of Aptamers and Nanomaterials

Biosensors
The unchecked and uncontrolled global spread of multidrug-resistant (MDR) bacteria is a serious challenge to healthcare and modern medicine, and demands diagnostic approaches that are rapid, sensitive, multiplexed, and reliable in point-of-care (POC ...
Kamna Ravi, Baljit Singh
doaj   +1 more source

Price Markups and Upstreamness in World Input-Output Data

Acta Universitatis Sapientiae: Economics and Business, 2021
This research uses the publicly available World Input-Output Database (WIOD) to investigate the relationship between an industry’s markup and its upstreamness, the industry’s position in the vertical chain of production; the research also identifies ...
Colonescu Constantin
doaj   +1 more source

Dicentrine, an Aporphine Alkaloid From Ocotea langsdorffii, Induces Mitochondrial Dysfunction and Oxidative Stress in Leishmania (L.) infantum

Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.
Dicentrine, an aporphine alkaloid, exhibits potent in vitro antileishmanial activity against Leishmania species with high selectivity and low macrophage cytotoxicity. Mechanistic studies reveal that the compound triggers parasite death possibly by inducing mitochondrial membrane disruption and oxidative stress.
Camila S. de Freitas, Eduardo Oliveira S. da Silva, Daniela C. Tristão, Guilherme M. Antar, Daniela P. Lage, Dóris M. Abrão, Luciana M. Ribeiro Antinarelli, Elaine S. Coimbra, João Henrique G. Lago, Eduardo A. F. Coelho   +9 more
wiley   +1 more source

Population Pharmacokinetic and Exposure‐Response Analysis of Vancomycin Nephrotoxicity in Cystic Fibrosis Patients

Pediatric Pulmonology, Volume 61, Issue 8, August 2026.
ABSTRACT Introduction Acute pulmonary exacerbations (APE) in persons with cystic fibrosis (PwCF) are associated with a reduction in long‐term pulmonary function. Vancomycin is recommended as first‐line treatment of methicillin‐resistant Staphylococcus aureus ‐APE in PwCF.
Jessica Barry, J. G. C. van Hasselt, Michael Evans, Elizabeth B. Hirsch, Jordan Dunitz, Sarah Shockley, Joanne Billings, Sílvia M. Illamola   +7 more
wiley   +1 more source

Integrated Model of Demand for Telephone Services in Terms of Microeconometrics

Folia Oeconomica Stetinensia, 2016
The paper presents the results of the testing effectiveness of the integrated model in the short-term forecasting of demand for telephone services in 24-hour cycles.
Kaczmarczyk Paweł
doaj   +1 more source

A review of the relationship between dimensions of alcohol consumption and the burden of disease: 2026 update including Mendelian randomisation studies

Addiction, Volume 121, Issue 8, Page 1998-2018, August 2026.
Abstract Background and aims Evidence on the causal impact and corresponding risk relationships between dimensions of alcohol consumption and health outcomes continues to evolve, with some contradictory findings across study designs. This review aimed to update current knowledge on causality and risk relationships to inform global and national ...
Sinclair Carr, Ana Lucia Espinosa Dice, Gerhard E. Gmel Sr., Ahmed S. Hassan, Kevin D. Shield, Jürgen Rehm   +5 more
wiley   +1 more source

Pharmacokinetic Drug–Drug Interactions of Imlunestrant in Healthy Female Participants of Nonchildbearing Potential

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Imlunestrant is a next‐generation, oral, selective estrogen receptor degrader approved for treating adults with estrogen receptor‐positive, human epidermal growth factor receptor 2‐negative, ESR1‐mutated advanced/metastatic breast cancer. Imlunestrant is metabolized partly by cytochrome P450 (CYP)3A4 oxidation and conjugation with glucuronic ...
Amita Datta‐Mannan, Elaine Shanks, Eunice Yuen, Vivian Rodriguez Cruz, Xuejing Aimee Wang, Stephen David Hall   +5 more
wiley   +1 more source

Leisure time and labor productivity: a new economic view rooted from sociological perspective

Economics: Journal Articles, 2019
Most economists measure labor productivity based on activities conducted at places of work and do not consider leisure time in their calculations. In contrast, psychologists and sociologists argue that leisure has a positive role in the production ...
Cui Dan, Wei Xiang, Wu Dianting, Cui Nana, Nijkamp Peter   +4 more
doaj   +1 more source

Labor Induction Versus Expectant Management—A Scoping Review of Randomized Controlled Trial Evidence

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 8, August 2026.
ABSTRACT Background Induction of labor is increasingly used across diverse obstetric indications, yet uncertainty persists regarding its impact on neonatal outcomes compared with expectant management across gestational ages. This scoping review aimed to map the scope, characteristics, and findings of randomized controlled trial (RCT) evidence comparing
Premanjali Chowdhury, Ilari Kuitunen
wiley   +1 more source

Abscopal Effect in Non-injected Tumors Achieved with Cytokine-Armed Oncolytic Adenovirus

Molecular Therapy: Oncolytics, 2018
Cancer treatment with local administration of armed oncolytic viruses could potentially induce systemic antitumor effects, or the abscopal effect, as they self-amplify in tumors, induce danger signaling, and promote tumor-associated antigen presentation.
Riikka Havunen, João M. Santos, Suvi Sorsa, Tommi Rantapero, Dave Lumen, Mikko Siurala, Anu J. Airaksinen, Victor Cervera-Carrascon, Siri Tähtinen, Anna Kanerva, Akseli Hemminki   +10 more
doaj   +1 more source