Results 111 to 120 of about 4,178 (152)

A Biweekly GLP‐1R Agonist Designed With Drug‐Free Intervals for Enhanced Efficacy, Receptor Homeostasis and Gastrointestinal Tolerability

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding   +4 more
wiley   +1 more source

Ultra-high piezoelectric properties of BiFeO3–BaTiO3 lead-free piezoelectric ceramics enabled by a one-step sintering process

open access: yesJournal of Advanced Ceramics
BiFeO3–BaTiO3 ceramics have been shown to possess considerable promise in the domain of high-temperature lead-free piezoelectric applications, a property attributable to their elevated Curie temperature and superior piezoelectric properties. However, the
Shiyuan Zhang   +8 more
doaj   +1 more source

Rearing Istocheta aldrichi (Diptera: Tachinidae) From Field‐Collected Japanese Beetles (Popillia japonica): 1. Methods to Improve Insect Collection and Parasitoid Pupariation

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
We describe methods for collecting and rearing the tachinid parasitoid Istocheta aldrichi from parasitized Japanese beetle adults. Hosts can be collected by hand and reared in the laboratory, or by using modified trap containers with added plant material and substrate to provide suitable conditions for I.
Simon Legault   +3 more
wiley   +1 more source

Stacking the Deck to Make Materials With Atypically Short Heterometallic d8 M(II)···Au(III) Bonds

open access: yesAngewandte Chemie, Volume 138, Issue 37, 7 September 2026.
Tetracyanoplatinate(II) and tetracyanoaurate(III), through self‐assembly in the presence of KCl, crystallize from water to form a one‐dimensional chain featuring the first reported PtII···AuIII metallophilic interaction with a very short distance of ∼3.0 Å between the metal centers.
Leanna M. Karn   +6 more
wiley   +2 more sources

Morphotropic Phase Boundary in Graft Poly(Vinylidene Fluoride‐co‐Tetrafluoroethylene) With High Curie Temperature

open access: yesAdvanced Science
Morphotropic phase boundary (MPB) has been demonstrated in various ferroelectric polymers near which piezoelectric coefficient d33 is substantially enhanced.
Zekai Fei   +6 more
doaj   +1 more source

Directional information flow in human frataxin defines allosteric pathways connecting the hydrophobic core to the iron‐binding ridge

open access: yesThe FEBS Journal, EarlyView.
Human frataxin deficiency causes Friedreich's ataxia, yet how iron‐binding events are communicated across the protein is unclear. Using transfer entropy analysis of molecular dynamics simulations, we identify buried hydrophobic core leucines (LEU136, LEU140) as the source of directional signaling toward the iron‐binding acidic ridge.
Kevser Kübra Kırboğa   +1 more
wiley   +1 more source

La renta diferencial agrícola en Argentina en 1986-2008, con datos de panel y co-integración

open access: yesEconómica, 2015
Ajustamos un modelo de renta diferencial de la tierra por departamento agrícola para 1986-2008 en Argentina. Utilizamos co-integración y datos en panel diferenciados por los aproximadamente 450 departamentos fértiles del país según cultivo. Estimaciones
Ana G. Bus, José L. Nicolini Llosa
doaj  

Desmin is not ubiquitously expressed in head and neck muscle fibers

open access: yesJournal of Anatomy, EarlyView.
Desmin is not ubiquitously expressed in human head and neck muscle fibers. A subset of fibers showed absent or very weak desmin immunoreactivity, with corresponding reduction or absence of desmin mRNA expression. Abstract Desmin, a major muscle‐specific intermediate filament protein, is widely regarded as a ubiquitous component of mature skeletal ...
Per Stål   +3 more
wiley   +1 more source

Heterogeneous layer-structured multiphase composite piezoelectret: Fabrication, piezoelectric performance, and application in electromechanical transduction

open access: yesAIP Advances
Piezoelectrets exhibit large piezoelectric sensitivity and high mechanical flexibility, widely employed in sensors, actuators, energy harvesters, etc. In this paper, a heterogeneous-structured multiphase composite piezoelectret (MPCP) was prepared using ...
Shiyu Wu   +4 more
doaj   +1 more source

Revealing the real high temperature performance and depolarization characteristics of piezoelectric ceramics by combined in situ techniques

open access: yes, 2018
Polarization variation in a thermal cycle and in situ HT d33 revealed real depolarization temperature and distinct d33 recovery.
Chengcheng Huang   +4 more
core   +1 more source

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