Results 11 to 20 of about 19,316 (153)
A new view of missense mutations in α-mannosidosis using molecular dynamics conformational ensembles. [PDF]
Protein SciAbstract The mutation of remote positions on enzyme scaffolds and how these residue changes can affect enzyme catalysis is still far from being fully understood. One paradigmatic example is the group of lysosomal storage disorders, where the enzyme activity of a lysosomal enzyme is abolished or severely reduced.
Mandl Š +10 more
europepmc +2 more sources
Acetylcholinesterase: Structure, dynamics, and interactions with organophosphorus compounds. [PDF]
Protein SciAbstract Acetylcholinesterase (AChE) is an enzyme that hydrolyzes the neurotransmitter acetylcholine (ACh), removing it from the synaptic cleft after the transmission of an electrical signal, making it an essential component of chemical neurotransmission. AChE is a serine hydrolase, containing a catalytic triad of Ser/His/Glu.
Hung LW +3 more
europepmc +2 more sources
The concept of political instability in economic research
International Journal of Management and Economics, 2021 This article reviews the use of the concept of political instability in economic research, the importance of which has been growing in recent years due to its potentially profound economic consequences.
Jannils Łukasz
doaj +1 more source
D74. Comparative Effectiveness Analysis of Ventral Hernia Repair with Panniculectomy: Evaluating Efficacy With and Without External Oblique Release [PDF]
Plastic and Reconstructive Surgery, Global OpenChris Amro, MD +7 more
doaj +2 more sources
Violent conflicts and state capacity: Evidence from Sub-Saharan Africa
Journal of Government and Economics, 2021 This paper investigates the impacts of conflicts on state-capacity in Sub-Saharan Africa (SSA), a region that has recorded a disproportionate number of armed conflicts and has a high presence in the Fragile States Index rankings.
Adedoyin Babajide +2 more
doaj +1 more source
Agronomy, 2022 Orobanche cumama wallr. is the sunflower root parasitic weed with special life stage in which seed germination and parasitism take place in the soil. In practice, applying microbial agents and trapping crop rotation are utilized separately, or just one ...
Jiao Xi +8 more
doaj +1 more source
Diversity, 2021 Streptomyces partum Act12 and Streptomyces roche D74 are biocontrol strains that can promote plant growth and enhance stress resistance in different crops. However, their effects on the rhizosphere microbiome and the role of the reassembled microbiome in
Yanjiang Zhang +6 more
doaj +1 more source
Multilinear morphisms between 1-motives [PDF]
, 2007 Let S be an arbitrary scheme. We define biextensions of 1-motives by 1-motives which we see as the geometrical origin of morphisms from the tensor product of two 1-motives to a third one. If S is the spectrum of a field of characteristic 0, we check that
Bertolin, Cristiana
core +8 more sources
Frontiers in Microbiology, 2021 We recently reported that the PPIase Par14 and Par17 encoded by PIN4 upregulate HBV replication in an HBx-dependent manner by binding to conserved arginine–proline (RP) motifs of HBx.
Umar Saeed +19 more
doaj +1 more source
SARS-CoV-2 diagnostic diary: from rumors to the first case. Early reports of molecular tests from the military research and diagnostic institute of Rio de Janeiro [PDF]
Memorias do Instituto Oswaldo Cruz, 2020 Corona virus disease (COVID-19) presents a serious threat to global health. A historical timeline of early molecular diagnostics from government alert (January 22) (D) was presented. After in silico analysis, Brazilian Army Institute of Biology (IBEx-RJ)
Marcio da Costa Cipitelli +10 more
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