Microglia Polarization with M1/M2 Phenotype Changes in rd1 Mouse Model of Retinal Degeneration [PDF]
Frontiers in Neuroanatomy, 2017 Microglia activation is recognized as the hallmark of neuroinflammation. However, the activation profile and phenotype changes of microglia during the process of retinal degeneration are poorly understood.
Tian Zhou, Zijing Huang, Xiaowei Sun
exaly +3 more sources
Pharmacokinetics and Pharmacodynamics of Intramuscular and Oral Betamethasone and Dexamethasone in Reproductive Age Women in India [PDF]
Clinical and Translational Science, Volume 13, Issue 2, Page 391-399, March 2020., 2020 High‐dose betamethasone and dexamethasone are standard of care treatments for women at risk of preterm delivery to improve neonatal respiratory and mortality outcomes. The dose in current use has never been evaluated to minimize exposures while assuring efficacy.
Alan H. Jobe +3 more
wiley +2 more sources
Gene therapy restores vision in rd1 mice after removal of a confounding mutation in Gpr179 [PDF]
Nature Communications, 2015 The rd1 mouse with a mutation in the Pde6b gene was the first strain of mice identified with a retinal degeneration. However, AAV-mediated gene supplementation of rd1 mice only results in structural preservation of photoreceptors, and restoration of the ...
Koji M Nishiguchi +2 more
exaly +2 more sources
Variable phenotypic expressivity in inbred retinal degeneration mouse lines: A comparative study of C3H/HeOu and FVB/N rd1 mice. [PDF]
Mol Vis, 2015 PURPOSE Recent advances in optogenetics and gene therapy have led to promising new treatment strategies for blindness caused by retinal photoreceptor loss.
van Wyk M, Schneider S, Kleinlogel S.
europepmc +1 more source
BMI1 loss delays photoreceptor degeneration in Rd1 mice. Bmi1 loss and neuroprotection in Rd1 mice
, 2006 Retinitis pigmentosa (RP) is a heterogeneous group of genetic disorders leading to blindness, which remain untreatable at present. Rd1 mice represent a recognized model of RP, and so far only GDNF treatment provided a slight delay in the retinal ...
van Lohuizen, Maarten +7 more
core +3 more sources
The effect of biopolymer gel derived from sugarcane on healing of traumatic oral ulcers: an experimental study [PDF]
Acta Cirúrgica BrasileiraPurpose: The extracellular polysaccharide (EPS) is produced by the bacterium Zoogloea sp. and plays a positive role in tissue repair. The purpose of this study was to clinically and histologically compare the effects of EPS in the healing of traumatic ...
Lívia Mirelle Barbosa +8 more
doaj +1 more source
, 2005 Currently much attention is focused on glutathione S transferase (GST)-induced suppression of apoptosis. The objective of our studies was therefore to see if GST isoenzymes rescue photoreceptors in retinal explants from rd1/rd1 mice, in which ...
Ekström, Per, +5 more
core +2 more sources
Acute abdomen after vertebroplasty-A rare complication
Frontiers in Surgery, 2023 IntroductionIn recent years, as the concept of minimally invasive treatment has been accepted by the majority of patients, the application of percutaneous vertebroplasty in osteoporotic vertebral compression fractures has gradually increased, and ...
Xiao-ming Zhao +3 more
doaj +1 more source
Classification of and individual treatment strategies for complex tethered cord syndrome
Frontiers in SurgeryObjectiveTo study the classification, diagnosis, and treatment strategies of complex tethered cord syndrome (C-TCS) on the basis of the patients’ clinical symptoms, imaging findings, and therapeutic schedule.MethodsThe clinical data of 126 patients with ...
Hepu Lin +6 more
doaj +1 more source
Frontiers in SurgeryBackgroundAdjacent segmental degeneration after lumbar fusion is one of the common long-term complications after lumbar fusion. With the continuous development of adjacent segmental degeneration, patients who fail conservative treatment often need ...
Tingxin Zhang +4 more
doaj +1 more source