Results 11 to 20 of about 192,491 (208)

The Phosphoproteome of the Rd1 Mouse Retina, a Model of Inherited Photoreceptor Degeneration, Changes after Protein Kinase G Inhibition

International Journal of Molecular Sciences, 2023
Retinitis pigmentosa (RP) is a frequent cause of blindness among the working population in industrial countries due to the inheritable death of photoreceptors. Though gene therapy was recently approved for mutations in the RPE65 gene, there is in general
Jiaming Zhou, C. Welinder, P. Ekström
semanticscholar   +1 more source

Morphology and Particle Size of a Synthesized NMC 811 Cathode Precursor with Mixed Hydroxide Precipitate and Nickel Sulfate as Nickel Sources and Comparison of Their Electrochemical Performances in an NMC 811 Lithium-Ion Battery

Energies, 2022
Cathode precursors of lithium-NMC 811 were synthesized by the coprecipitation method using two different nickel sources, namely mixed nickel–cobalt hydroxide precipitate (MHP) and nickel sulfate.
A. S. Wijareni, H. Widiyandari, A. Purwanto, A. F. Arif, M. Z. Mubarok   +4 more
semanticscholar   +1 more source

Inhibition of the MAPK/c-Jun-EGR1 Pathway Decreases Photoreceptor Cell Death in the rd1 Mouse Model for Inherited Retinal Degeneration

International Journal of Molecular Sciences, 2022
Retinitis pigmentosa (RP) is a group of inherited retinal dystrophies that typically results in photoreceptor cell death and vision loss. Here, we explored the effect of early growth response-1 (EGR1) expression on photoreceptor cell death in Pde6brd1 ...
Yujie Dong, Wenrong Xu, Yan Li, Chun-jiang Wei, Yunzhang Hu, Z. Hu, F. Paquet-Durand, K. Jiao   +7 more
semanticscholar   +1 more source

Surface Coating of NCM-811 Cathode Materials with g-C3N4 for Enhanced Electrochemical Performance

ACS Omega, 2022
Li(Ni0.8, Co0.1, Mn0.1)O2 (NCM-811) cathode materials have been commercialized recently, aiming to increase the specific capacity and specific energy of the lithium-ion battery for practical applications in electric vehicles. The surface coating has been
Sheng-Xiong She, Yangfan Zhou, Zijian Hong, Yuhui Huang, Yongjun Wu   +4 more
semanticscholar   +1 more source

Multi-omics analyses reveal early metabolic imbalance and mitochondrial stress in neonatal photoreceptors leading to cell death in Pde6brd1/rd1 mouse model of retinal degeneration.

Human Molecular Genetics, 2022
Retinal diseases exhibit extensive genetic heterogeneity and complex etiology with varying onset and severity. Mutations in over 200 genes can lead to photoreceptor dysfunction and/or cell death in retinal neurodegeneration.
Ke Jiang, A. Mondal, Yogita K. Adlakha, Jessica D. Gumerson, A. Aponte, L. Gieser, Jung-Woong Kim, Alexis Boleda, M. Brooks, Jacob Nellissery, D. Fox, R. Balaban, R. Covian, A. Swaroop   +13 more
semanticscholar   +1 more source

The effects of ambient storage conditions on the structural and electrochemical properties of NMC-811 cathodes for Li-ion batteries

, 2021
High-Ni cathode materials are prone to reactivity and instability upon exposure to ambient levels of humidity. This has implications for the storage and processing of cathodes for Li-ion batteries (LIBs), in order to avoid any premature degradation of ...
Chiara Busà, Meltiani Belekoukia, M. Loveridge   +2 more
semanticscholar   +1 more source

First-line pembrolizumab/placebo plus trastuzumab and chemotherapy in HER2-positive advanced gastric cancer: KEYNOTE-811

Future Oncology, 2020
Treatment options for patients with HER2-positive advanced gastric cancer are limited, and the prognosis for these patients is poor. Pembrolizumab has demonstrated promising antitumor activity in patients with advanced gastric or gastroesophageal ...
H. Chung, Y. Bang, Charles S Fuchs, S. Qin, T. Satoh, K. Shitara, J. Tabernero, E. Cutsem, M. Alsina, Z. Cao, Jia Lu, P. Bhagia, C. Shih, Y. Janjigian   +13 more
semanticscholar   +1 more source

Inhibition of mTOR signaling by rapamycin protects photoreceptors from degeneration in rd1 mice

Zoological Research, 2021
Retinitis pigmentosa (RP) is an inherited retinal degenerative disease that begins with defective rod photoreceptor function, followed by impaired cone function, and complete blindness in its late stage.
Jialiang Yang, Tongdan Zou, Fang Yang, Zhenglin Yang, Houbin Zhang   +4 more
semanticscholar   +1 more source

Long-Term Cyclability of NCM-811 at High Voltages in Lithium-Ion Batteries: an In-Depth Diagnostic Study

, 2020
High-nickel layered oxides, such as LiNi0.8Co0.1Mn0.1O2 (NCM-811), offer higher energy density than their low-nickel counterparts at a given voltage and are gaining major traction in automotive lit...
Wangda Li, Xiaoming Liu, Q. Xie, Ya You, M. Chi, A. Manthiram   +5 more
semanticscholar   +1 more source

iPSC-Derived Retina Transplants Improve Vision in rd1 End-Stage Retinal-Degeneration Mice

Stem Cell Reports, 2017
Summary Recent success in functional recovery by photoreceptor precursor transplantation in dysfunctional retina has led to an increased interest in using embryonic stem cell (ESC) or induced pluripotent stem cell (iPSC)-derived retinal progenitors to ...
M. Mandai, Momo Fujii, Tomoyo Hashiguchi, Genshiro A. Sunagawa, Shin-ichiro Ito, Jianan Sun, Jun Kaneko, Junki Sho, Chikako Yamada, Masayo Takahashi   +9 more
semanticscholar   +2 more sources