Results 71 to 80 of about 1,351 (149)

Polo‐like kinase 1–inhibitor co‐complex structures via the surface‐entropy reduction approach and a DARPin‐assisted approach

open access: yesActa Crystallographica Section D, Volume 81, Issue 12, Page 718-733, December 2025.
A surface‐entropy reduction approach for human Polo‐like kinase 1 (PLK1) enabled a reproducible and robust crystallization system for this cancer drug target. Co‐crystal structures with representatives of three different small‐molecule inhibitor classes were elucidated.
Uwe Eberspaecher   +7 more
wiley   +1 more source

Xtricorder: a likelihood‐enhanced self‐rotation function and application to a machine learning‐enhanced Matthews prediction of asymmetric unit copy number

open access: yesActa Crystallographica Section D, Volume 81, Issue 12, Page 678-692, December 2025.
Xtricorder is a tool for analysing crystallographic data, featuring a likelihood‐enhanced self‐rotation function and a novel `composite‐section diagram' thereof, which aids interpretation and enables a machine learning‐enhanced prediction of asymmetric unit content.Analysis of crystallographic diffraction data after collection and integration but ...
Airlie J. McCoy, Randy J. Read
wiley   +1 more source

Compensation Costs for Work Related Accidents in Polish Agriculture

open access: yesZagadnienia Ekonomiki Rolnej
The intent of this study is to discern the level and trend of compensation costs resulting from work related accidents in Poland’s agriculture sector.
Zielińska Anetta
doaj   +1 more source

Completion of partial structures using Patterson maps with the CrysFormer machine‐learning model

open access: yesActa Crystallographica Section D, Volume 81, Issue 12, Page 668-677, December 2025.
We integrate existing machine learning‐based protein structure‐prediction methods with X‐ray crystallography by completing partial structures derived from AlphaFold predictions and the corresponding Patterson map information. The CrysFormer results are promising when applied to an initial data set of 15‐residue fragments in P21 unit cells.Protein ...
Tom Pan   +4 more
wiley   +1 more source

Identifying Selected Behavioral Determinants of Risk and Uncertainty on the Real Estate Market

open access: yesReal Estate Management and Valuation, 2014
Various market behaviors can be characterized as risky or uncertain, thus their observation is important to the real estate market system. The extensive use of behavioral factors facilitates their implementation and studies in relation to the real estate
Brzezicka Justyna, Wisniewski Radoslaw
doaj   +1 more source

Structural rearrangements due to the E78D/E81D mutations.

open access: yes, 2013
The side chains of the E/D78 and E/D81 residues in the wild-type and the mutated HbpS point towards the corresponding side chains from a neighboring monomer in the octameric assembly. The distance of the two E81 side chains in the wild-type protein (gray)
Ina Wedderhoff (450979)   +3 more
core   +1 more source

Analyzing the Adoption of Green Taxi Services: A Multi-Stakeholder Perspective

open access: yesECONOMICS
Vehicle emissions are a major contributor to urban air pollution, which poses significant health risks and contributes to environmental degradation.
Phu Nguyen Hoang   +3 more
doaj   +1 more source

Modeling Enterprise Risk Management Ecosystems Using Text Analytics

open access: yesFoundations of Management
In recent years, a paradigm shift in risk management has altered in a holistic way, which we call Enterprise Risk Management (ERM). ERM solves the limitations of Traditional Risk Management (TRM).
SAE-LIM Patipan
doaj   +1 more source

Editorial for the Special Issue: "Novel Solutions and Novel Approaches in Operational Research"

open access: yesBusiness Systems Research
This special issue of Business Systems Research (SI of the BSR) is being co-published by the Slovenian Society INFORMATIKA – Section for Operational Research (SSI -SOR). It focuses on recent advances in Operations Research and Management Science (OR / MS)
Drobne Samo   +2 more
doaj   +1 more source

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