Results 71 to 80 of about 1,148,539 (314)

Evidence of Cryptosporidium transmission between cattle and humans in northern New South Wales

, 2012
Cryptosporidium is an enteric parasite of public health significance that causes diarrhoeal illness through faecal oral contamination and via water. Zoonotic transmission is difficult to determine as most species of Cryptosporidium are morphologically ...
Kemp, R., McKinnon, B., Walker, B., McKinnon, Bob, Ryan, Una, Ng, Josephine Su Yin, Eastwood, K., Porigneaux, P., Eastwood, Keith, Miller, David, Walker, Belinda, Bramley, E., Durrheim, David N., Laurie, Kate, Kemp, Ross, Bramley, Elizabeth, Ng, J.S.Y., Laurie, K., Ryan, U., Miller, D., Porigneaux, Philippe, Massey, P.D., Durrheim, D.N., Massey, Peter D.   +23 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Measurement of Plasmodium falciparum transmission intensity using serological cohort data from Indonesian schoolchildren. [PDF]

, 2013
BACKGROUND: As malaria transmission intensity approaches zero, measuring it becomes progressively more difficult and inefficient because parasite-positive individuals are hard to detect. This situation may arise shortly before achieving local elimination,
Lobo, Neil F, William A Hawley, Drakeley, Chris J, Jackie Cook, Supargiyono, Supargiyono, Wijayanti, Mahardika A, Dian Nugraheni, Supargiyono Supargiyono, Neil F Lobo, Anis N Widyastuti, Widyastuti, Anis N, Hawley, William A, Michael T Bretscher, Cook, Jackie, Bretscher, Michael T, Nugraheni, Dian, Mahardika A Wijayanti, Chris J Drakeley   +17 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Seasonal variations in Nigeria: understanding COVID-19 transmission dynamics and immune responses

Journal of Global Health Reports, 2020
There is a global rise in the emergence of infectious diseases and the enigmatic coronavirus disease 2019 (COVID-19) being the most recent one. It is ravaging the world with little understanding of its etiology and factors affecting its transmission ...
Oluwamuyiwa A. Ayanshina, Adeleye O. Adeshakin, Lukman O. Afolabi, Funmilayo O. Adeshakin, Ganiyu O. Alli-Balogun, Dehong Yan, Samuel Essien-Baidoo, Xiaochun Wan   +7 more
doaj   +1 more source

Tuberculosis transmission attributable to close contacts and HIV status, Malawi. [PDF]

, 2006
We conducted the first molecular study of tuberculosis (TB) to estimate the role of household contact and transmission from HIV-positive putative source contacts (PSCs) in a high HIV-prevalence area.
Yates, Malcolm D, Traore, Hamidou, Judith R. Glynn, Hamidou Traore, Michael Mwenebabu, Fine, Paul E.M., Glynn, Judith R., Mwenebabu, M, Glynn, Judith R, Crampin, Amelia C, Mwenebabu, Michael, Mwaungulu, Lorren, Drobniewski, FD, Amelia C. Crampin, Mwaungulu, L, Sian Floyd, Fine, Paul EM, Traoré, H, Paul E.M. Fine, Crampin, Amelia C., Chaguluka, SD, Floyd, Sian, Yates, Malcolm D., Chaguluka, Steven D, Lorren Mwaungulu, Steven D. Chaguluka, Malcolm D. Yates, Drobniewski, Francis, Glynn, JR, Yates, MD, Crampin, AC, Chaguluka, Steven D., Francis Drobniewski, Fine, PEM, Floyd, S   +34 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Transcriptome Analyses of Diaphorina citri Midgut Responses to Candidatus Liberibacter Asiaticus Infection

Insects, 2020
The Asian citrus psyllid (ACP), Diaphorina citri Kuwayama (Hemiptera: Liviidae), is an important transmission vector of the citrus greening disease Candidatus Liberibacter asiaticus (CLas). The D. citri midgut exhibits an important tissue barrier against
Hai-Zhong Yu, Ning-Yan Li, Xiang-Dong Zeng, Jian-Chun Song, Xiu-Dao Yu, Hua-Nan Su, Ci-Xiang Chen, Long Yi, Zhan-Jun Lu   +8 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source