Results 101 to 110 of about 313,257 (304)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Impact of Current Uncertainties in the 12C+12C Nuclear Reaction Rate on Intermediate-mass Stars and Massive White Dwarfs

open access: yesThe Astrophysical Journal
Recent determinations of the total rate of the ^12 C+ ^12 C nuclear reaction show non-negligible differences with the reference reaction rate commonly used in previous stellar simulations.
Francisco C. De Gerónimo   +8 more
doaj   +1 more source

A survey of pulsating DA and DB white dwarfs Observations with the Whole Earth Telescope

open access: yesEPJ Web of Conferences, 2017
White dwarfs represent the end point of stellar evolution for the majority of stars. As such, they are excellent astrophysical laboratories. They are structurally simple, with electron degenerate cores surrounded by thin surface layers of helium and/or ...
Provencal J. L.   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Follow-up Observations of Candidate White Dwarf Planets with MIRI

open access: yesThe Astronomical Journal
We report on second-epoch imaging of two candidate planet-hosting white dwarf (WD) stars, WD 2105−82 and WD 1202−232. Both stars showed evidence of resolved, planet-mass candidate companions in observations using the MIRI mid-infrared imager on JWST.
Fergal Mullally   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A NOÇÃO DE DESTINO NA ASTROLOGIA E SUA INFLUÊNCIA NO PENSAMENTO OCIDENTAL: NOTAS INSPIRADAS EM UMA LEITURA CRÍTICA DE THE STARS DOWN TO EARTH - T.W.ADORNO - DOI 10.5752/P.1983-2478.2014v9n16p374

open access: yesInterações, 2015
RESUMO Tomando como referência a crítica feita por T.W. Adorno, em sua obra The Stars down to Earth, à astrologia, caracterizada por ele como mera superstição, este artigo propõe-se a mostrar que, ao contrário dessa desqualificação, existe um ...
Vani Terezinha de Rezende
doaj   +1 more source

Know Your Neighborhood: A Detailed Model Atmosphere Analysis of Nearby White Dwarfs

open access: yes, 2012
We present improved atmospheric parameters of nearby white dwarfs lying within 20 pc of the Sun. The aim of the current study is to obtain the best statistical model of the least-biased sample of the white dwarf population.
Bergeron   +62 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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