Results 101 to 110 of about 313,257 (304)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Recent determinations of the total rate of the ^12 C+ ^12 C nuclear reaction show non-negligible differences with the reference reaction rate commonly used in previous stellar simulations.
Francisco C. De Gerónimo +8 more
doaj +1 more source
A survey of pulsating DA and DB white dwarfs Observations with the Whole Earth Telescope
White dwarfs represent the end point of stellar evolution for the majority of stars. As such, they are excellent astrophysical laboratories. They are structurally simple, with electron degenerate cores surrounded by thin surface layers of helium and/or ...
Provencal J. L. +2 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Follow-up Observations of Candidate White Dwarf Planets with MIRI
We report on second-epoch imaging of two candidate planet-hosting white dwarf (WD) stars, WD 2105−82 and WD 1202−232. Both stars showed evidence of resolved, planet-mass candidate companions in observations using the MIRI mid-infrared imager on JWST.
Fergal Mullally +8 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
RESUMO Tomando como referência a crítica feita por T.W. Adorno, em sua obra The Stars down to Earth, à astrologia, caracterizada por ele como mera superstição, este artigo propõe-se a mostrar que, ao contrário dessa desqualificação, existe um ...
Vani Terezinha de Rezende
doaj +1 more source
Know Your Neighborhood: A Detailed Model Atmosphere Analysis of Nearby White Dwarfs
We present improved atmospheric parameters of nearby white dwarfs lying within 20 pc of the Sun. The aim of the current study is to obtain the best statistical model of the least-biased sample of the white dwarf population.
Bergeron +62 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

