Results 121 to 130 of about 4,822,469 (343)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Um estudo da abundância de lítio, rotação, atividade cromosférica e magnetismo das estrelas análogas e gêmeas solares [PDF]
, 2013 The study physical process that control the stellar evolution is strength influenced by several stellar parameters, like as rotational velocity, convective envelope mass deepening, and magnetic field intensity.
Costa, Jefferson Soares da
core
Young stars forming in the galactic center
, 2011 Educação Superior::Ciências Exatas e da Terra::AstronomiaThis image shows the formation of three stars and their movements inside of the Milky Way.
Jet Propulsion Laboratory +2 more
core +1 more source
Magnetic White Dwarfs from DESI
The Astrophysical JournalA significant fraction of white dwarfs, the degenerate remnants of low- and intermediate-mass stars, host strong magnetic fields; yet the origin and evolution of these magnetic fields remain poorly understood.
L. L. Amorim +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A influência da cultura da organização na aprendizagem de executivos: o caso da Tigre [PDF]
, 2005 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção.Os objetos de estudo desta tese são a aprendizagem gerencial no ambiente de trabalho e o modo como a cultura da organização,
Possamai, Fabíola
core
Young stars forming in the galactic center
, 2016 Educação Superior::Ciências Exatas e da Terra::AstronomiaThis image shows the formation of three stars and their movements inside of the Milky Way.
National Aeronautics and Space Administration (NASA) +2 more
core +1 more source
The Astrophysical JournalWD J005311 is the peculiar stellar remnant of the Galactic supernova from 1181, and appears to have been the merger of two white dwarfs. We present time-resolved spectroscopy of WD J005311 showing emission line variability on a wide range of timescales ...
C. Alexander Thomas +4 more
doaj +1 more source
Naturalistas viajantes Travel naturalists
História, Ciências, Saúde: Manguinhos, 1995 O naturalista viajante é aquele que nos séculos XVIII e XIX dedicava-se ao estudo da história natural, ou seja, da natureza, compreendendo os astros, o ar, os animais, os vegetais e minerais da superfície e da profundidade da terra.
Miriam L. Moreira Leite
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source