Results 171 to 180 of about 4,822,469 (343)
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Baby stars in the North America nebula
Educação Superior::Ciências Exatas e da Terra::AstronomiaThis image shows the stars of the North America nebula in all its stages of ...
Jet Propulsion Laboratory +2 more
core
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
JWST Directly Images Giant Planet Candidates Around Two Metal-polluted White Dwarf Stars
We report the discovery of two directly imaged, giant planet candidates orbiting the metal-rich, hydrogen atmosphere white dwarfs WD 1202−232 and WD 2105−82. JWST’s Mid-Infrared Instrument (MIRI) data on these two stars show a nearby resolved source at a
Susan E. Mullally +11 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Doppler Effect, binary stars, neutron stars and black holes
Educação Superior::Ciências Exatas e da Terra::FísicaHarmonic motionDoppler shift is introduced with sound waves, then extended to electromagnetic waves (radiation). The Doppler shift of stellar spectral lines and/or pulsar frequencies provides a measure
Lewin, Walter
core

