Results 191 to 200 of about 4,822,469 (343)

SPINAL DISORDERS IN PROFESSIONAL ESPORTS ATHLETES: PROTOCOL FOR A SYSTEMATIC REVIEW. [PDF]

Acta Ortop Bras
Miachiro NY, de Menezes MD, Pontes MDS, Herrero CFPDS.   +3 more
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

The effect of metabolic bariatric surgery on Anti-Müllerian hormone levels: a systematic review and meta-regression analysis. [PDF]

BMC Endocr Disord
Mehdinezhad Roshan M, Davaryari N, Cheshmi F, Pouya P, Moradian SA, Sohouli MH, Hajpour H, Novin MS, Oskouei BS, da Silva Magalhães EI.   +9 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Does endodontic treatment modify serum inflammatory markers of cardiovascular risk in individuals with asymptomatic apical periodontitis? a systematic review and meta-analysis. [PDF]

Clin Oral Investig
Silva Araújo R, Abreu Fonseca Thomaz EB, da Silva Magalhães EI, Balbinot Hilgert J, Carvalho Souza SF.   +4 more
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Quantitative Analysis of Polymers by MALDI-TOF Mass Spectrometry: Correlation Between Signal Intensity and Arm Number. [PDF]

J Mass Spectrom
Dalgic MS, Kumar S, Weidner SM.
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Zinc abundances in galactic bulge stars

, 2013
Zinc is overabundant in metal-poor stars (Cayrel et\ud al. 2004), being partially produced by neutron addition.\ud It decreases with increasing metallicity, similarly\ud to alpha-elements.
Barbuy, Beatriz Leonor Silveira, Silveira, Carlos Roberto da   +1 more
core  

Best practices on blood and blood products for a prehospital hemorrhage protocol: consensus from the 2025 Canadian prehospital transfusion summit. [PDF]

Scand J Trauma Resusc Emerg Med
Peddle M, Greene A, Trojanowski J, Shih AW, Chang E, Nahirniak S, Pearson D, Prokopchuk-Gauk O, Martin D, Froh J, Musuka C, Seidl C, Lin Y, MacDonald S, Richards L, Farrell M, Miller D, Mack J, Da Luz L, Drennan IR, Singh K, Shingala D, Nolan B.   +22 more
europepmc   +1 more source