Results 211 to 220 of about 313,257 (304)

Microsurgery Versus Radiosurgery for Vestibular Schwannoma: Which Approach Yields Better Long-Term Results? [PDF]

Cureus
Olvera Morales M, Morales Castillo I, Pelayo Fernández J, Polania Pérez ON, Robles Illescas JA, Villar Vilchis AN, Valdez Mendoza ED, Ducoing Castillo JF, Frank Nuñez JJ, Ortiz Hernández MA, Sánchez Fernández MA, Ramirez Molina DA, Fuentes Reyes CM, Flores Valdés JR.   +13 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Protocol for fixation and staining of postmortem human brain tissue optimized for focused ion beam-scanning electron microscopy. [PDF]

STAR Protoc
Maier MJ, Lewis DA, Freyberg Z, Glausier JR.   +3 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Drusen-specific dark adaptation profiles in intermediate age-related macular degeneration. [PDF]

Int J Retina Vitreous
Forte P, Ferro Desideri L, Nassisi M, Milanesi F, Feo A, Bagnasco I, Iglesia SM, Forte G, Scandella D, Roccatagliata F, Fontana V, Eandi CM, Iester M, Jolly JK, Zinkernagel MS, Viola F, Nicolò M.   +16 more
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Interactive Conversational Agents to Improve Dietary Behaviors for Health Promotion: Mixed Systematic Review.

J Med Internet Res
Amil S, Gagnon MP, Bédard A, Da SMAR, Zavala Mora D, Drapeau V, Desroches S.   +6 more
europepmc   +1 more source

Tracking a misclassified pathogen: genomic and epidemiological features of <i>Vibrio paracholerae</i>. [PDF]

Microb Genom
Morgado SM, Fonseca ELD, Vicente ACP.
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Injectable living hydrogel as engineered biotherapeutic to promote tooth-extraction wound healing and alveolar bone regeneration. [PDF]

Bioact Mater
Guo J, Lei W, Li B, Li K, Li J, Wang Z, Liu H, Huang C, Shen Y.   +8 more
europepmc   +1 more source