Results 91 to 100 of about 598 (153)

Fibrinogen-to-prealbumin and C-reactive protein-to-prealbumin ratios as prognostic indicators in severe fever with thrombocytopenia syndrome [PDF]

BackgroundThe primary aim of this study is to investigate the correlation between serum levels of fibrinogen-to-prealbumin ratio (FPR) and C-reactive protein-to-prealbumin ratio (CPR) and prognostic outcomes among patients with severe fever with ...
Fan Zhang, Jin-Ping Qiao, Wen-Tao He, Xiao-Yi Liu   +3 more
core   +1 more source

Co-Circulation of Tick-Borne Bandaviruses and Orthonairoviruses Across Humans, Livestock, and Rats in Pakistan: Serologic Evidence and Public Health Implications

Viruses
Tick-borne viruses (TBVs) pose significant public health and economic threats. Pakistan has endemic Crimean-Congo hemorrhagic fever virus (CCHFV), but evidence suggests broader TBV circulation.
Muhammad Ammar, Shengyao Chen, Muhammad Saqib, Jingyuan Zhang, Awais-Ur-Rahman Sial, Asad Zia, Yaohui Fang, Muhammad Khalid Mansoor, Abulimiti Moming, Asim Shahzad, Rehman Hafeez, Aneela Javed, Ali Hassan, Ben Hu, Ali Zohaib, Shu Shen, Fei Deng   +16 more
doaj   +1 more source

Multi-omics analysis of severe fever with thrombocytopenia syndrome virus infection in Rhipicephalus microplus cells reveals antiviral tick factors. [PDF]

The increasing prevalence of tick-borne arboviral infections worldwide necessitates advanced control strategies, particularly those targeting vectors, to mitigate the disease burden.
Brennan, Benjamin, Davies, Kelsey, Fares, Mazigh, Flory, Charlotte, Gu, Quan, Kohl, Alain, Lamont, Douglas, Petit, Marine, Sakyi, Lesley Bell-, Scaturro, Pietro, Score, Alan   +10 more
core   +1 more source

Suppression of Interferon Response and Antiviral Strategies of Bunyaviruses

Tropical Medicine and Infectious Disease
The order Bunyavirales belongs to the class of Ellioviricetes and is classified into fourteen families. Some species of the order Bunyavirales pose potential threats to human health.
Yingying He, Min Shen, Xiaohe Wang, Anqi Yin, Bingyan Liu, Jie Zhu, Zhenhua Zhang   +6 more
doaj   +1 more source

Machine learning for identifying risk of death in patients with severe fever with thrombocytopenia syndrome [PDF]

BackgroundSevere fever with thrombocytopenia syndrome (SFTS) has attracted attention due to the rising incidence and high severity and mortality rates. This study aims to construct a machine learning (ML) model to identify SFTS patients at high risk of ...
Jiale Guo, Qionghan He, Qiuping Dong, Zhaoru Zhang, Zihao You   +4 more
core   +1 more source

Development Of Novel Vaccination Strategies Against Emerging Bunyaviruses [PDF]

, 2022
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a highly pathogenic emergent bunyavirus. First isolated in 2009 in China, SFTSV is now endemic to several east Asian countries where high case fatality ratios of 6-30% are reported. The primary
Manzoni, Tomaz
core   +1 more source

Downregulation of transcription 1 hinders the replication of Dabie bandavirus by promoting the expression of TLR7, TLR8, and TLR9 signaling pathway

Ticks and Tick-borne Diseases
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a bunyavirus that causes SFTS, with a case fatality rate of up to 30 %. The innate immune system plays a crucial role in the defense against SFTSV; however, the impact of viral propagation of STFSV on the innate immune system remains unclear.
Hao An, Xiaoli Yu, Yumei Liu, Lei Fang, Ming Shu, Qingfeng Zhai, Junhao Chen   +6 more
openaire   +3 more sources

Serum calprotectin correlates with severity of severe fever with thrombocytopenia syndrome

Frontiers in Microbiology
IntroductionSevere fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by Dabie bandavirus (DBV), clinically characterized by fever, thrombocytopenia, and multiple organ dysfunction. Severe cases are often associated with
Shijie Cai, Jiahua Zhu, Zhiye Xu, Wenqin Chen, Yue Tao, Taihong Huang, Sen Wang, Sen Wang   +7 more
doaj   +1 more source

SNX11-Deletion Inhibit Dabie Bandavirus Infection by Interfering with the Synthesis of V-ATPase

SNX11, a sorting nexin protein localized on the endosomal membrane, is an important protein closely related to protein sorting and endosomal trafficking. Previously, through a genome-wide CRISPR screening, we identified SNX11 as a critical protein for the entry of Dabie bandavirus.
Tiezhu Liu, Xueqi Wang, Yang Fang, Ping Zhang, Qiang Sun, Jiandong Li, Shiwen Wang   +6 more
openaire   +1 more source

Early mortality risk prediction in severe fever with thrombocytopenia syndrome using an interpretable machine learning model based on routine clinical parameters

Frontiers in Public Health
BackgroundSevere Fever with Thrombocytopenia Syndrome (SFTS) is characterized by high mortality and rapid progression, necessitating accurate early prognosis to optimize supportive care.
Qian Dai, Ji Guo, Liangfei Xu, Qiong Lu, He Chen, Yuanyuan Hu, Ying Wang, Tong Tong   +7 more
doaj   +1 more source