Results 91 to 100 of about 542 (103)

Heterogeneity of lymphoid cells in PBMCs in the acute phase of SFTS: Single-cell transcriptome profiling. [PDF]

open access: yesJ Biomed Res
Zhao J   +12 more
europepmc   +1 more source

Diagnostic and Treatment Status of Severe Fever with Thrombocytopenia Syndrome in a Patient Cohort in 2022-2024. [PDF]

open access: yesJugan Geongang Gwa Jilbyeong
Kim M   +7 more
europepmc   +1 more source

Isolation and Quantification of Dabie bandavirus

Methods in Molecular Biology
Virus isolation is an important and critical method used for the diagnosis of emerging and re-emerging viral pathogens. The process involves the use of in vitro cell culture (most common) or suckling mice and relies on proper handling and storage of the samples prior to testing.
Diana, Fernández, Patricia V, Aguilar
exaly   +3 more sources

The implication of abnormal routine coagulation parameters in Dabie bandavirus infection

Scandinavian Journal of Clinical and Laboratory Investigation
Prolonged activated partial thromboplastin time (APTT) and thrombin time (TT), normal prothrombin time (PT) and elevated D-dimer level are typical manifestation of routine coagulation parameters in patients infected with Dabie bandavirus (DBV), infection-induced coagulation activation and consumption, and a heparin-like effect due to endogenous heparan
Ning Tang
exaly   +3 more sources

Coagulopathy in Dabie bandavirus infection is related to endogenous heparinoids release and mast cells activation

Thrombosis Research
The prolonged activated partial thromboplastin time (APTT) and thrombin time in patients infected with Dabie bandavirus (DBV) have been recognized to be poor prognostic indicators and attributed to a heparin-like effect rather than a decrease in coagulation factor levels.To clarify the correlation between endogenous heparinoids and coagulopathy in ...
Peihong Yuan, Ning Tang
exaly   +3 more sources

Development of a broad-spectrum multiepitope vaccine against dabie bandavirus through immunoinformatic approaches

International Immunopharmacology
Dabie bandavirus is an emerging tick-borne disease-causing high morbidity and mortality in East Asia, with no vaccines or targeted antiviral therapies. In this study, a multiepitope vaccine was designed using an immunoinformatic strategy to provide robust immune protection.
Ashwag Shami   +2 more
exaly   +3 more sources

Bergamottin, A Natural Bioactive Compound, Inhibits Dabie Bandavirus Infection In Vitro and In Vivo

Journal of Medical Virology
ABSTRACT Severe fever with thrombocytopenia syndrome (SFTS) is a novel, highly fatal disease caused by Dabie bandavirus (DBV), also referred to as severe fever with thrombocytopenia syndrome virus (SFTSV). DBV is endemic to many Asian countries, and its incidence has recently increased.

exaly   +3 more sources

Screening of immune epitope in the proteome of the Dabie bandavirus, SFTS, to design a protein-specific and proteome-wide vaccine for immune response instigation using an immunoinformatics approaches

Computers in Biology and Medicine, 2022
Tick-borne viruses are a major risk from tick bites, which could result in viral infectious diseases among animals and humans. Bunyavirus causes severe fever with thrombocytopenia syndrome (SFTS), with signs and symptoms including high fever, vomiting, diarrhea, thrombocytopenia (low platelet count), leukopenia (low white blood cell count), elevated ...
Muhammad Suleman   +11 more
openaire   +2 more sources

Phylogeographic Epidemiology of Dabie Bandavirus in East Asia: Divergent Transmission Networks and Genotype‑Linked Virulence

Background: Severe fever with thrombocytopenia syndrome (SFTS) exhibits marked geographic heterogeneity across East Asia. We aimed to investigate the evolutionary drivers and ecological determinants underlying the decoupling of SFTS incidence and clinical severity between inland and coastal regions.<br><br>Methods: We integrated 1,820 high ...
Letian Fang   +17 more
openaire   +1 more source

Tectorigenin Reduces Dabie bandavirus‐Induced Cytokine Storm by Regulating Toll‐Like Receptor 7/Extracellular Signal–Regulated Kinase Pathway

Chemical Biology & Drug Design
ABSTRACTSevere fever with thrombocytopenia syndrome (SFTS) is a severe emerging infectious disease caused by Dabie bandavirus (DBV). Tectorigenin has been demonstrated to exert anti‐inflammatory effect. Here, we aimed to investigate the effects of tectorigenin on DBV‐induced cytokine storm.
Qian Zhang   +13 more
openaire   +2 more sources

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