Results 21 to 30 of about 1,736 (138)

Effective treatment of advanced Oropouche virus, Rift Valley fever virus, and Dabie bandavirus infections with 4'-fluorouridine [PDF]

mBio
Oropouche virus (OROV), Rift Valley fever virus (RVFV), and Dabie bandavirus (DBV) are significant re-emerging and emerging human pathogens with major public health implications.
Jonna B. Westover, Kie Hoon Jung, Inioska Rojas, Kevin W. Bailey, Julio Landinez-Aponte, Gregory R. Blumeling, Shuli Mao, Alexander A. Kolykhalov, Michael G. Natchus, George R. Painter, Brian B. Gowen   +10 more
doaj   +4 more sources

Host factor MxA restricts Dabie bandavirus infection by targeting the viral NP protein to inhibit NP-RdRp interaction and ribonucleoprotein activity. [PDF]

Journal of Virology
ABSTRACT Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease with high case mortality rates, which is caused by Dabie bandavirus (DBV), a novel pathogen also termed as SFTS virus (SFTSV). Currently, no specific therapeutic drugs or vaccines are available for SFTS.
Yun-Jia Ning, Hualin Wang, Yuan-Qin Min
exaly   +4 more sources

The molecular evolution of Dabie bandavirus (Phenuiviridae: Bandavirus: Dabie bandavirus), the agent of severe fever with thrombocytopenia syndrome

Вопросы вирусологии, 2022
Since the Dabie bandavirus (DBV; former SFTS virus, SFTSV) was identified, the epidemics of severe fever with thrombocytopenic syndrome (SFTS) caused by this virus have occurred in several countries in East Asia. The rapid increase in incidence indicates
T. E. Sizikova, V. N. Lebedev, S. V. Borisevich   +2 more
doaj   +4 more sources

Dabie bandavirus infection induces macrophagic pyroptosis and this process is attenuated by platelets. [PDF]

PLoS Negl Trop Dis, 2023
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infection with a high mortality rate in humans, which is caused by Dabie bandavirus (DBV), formerly known as SFTS virus. Clinical manifestations of SFTS are characterized by high fever, thrombocytopenia, leukopenia, hemorrhage, gastrointestinal symptoms, myalgia and local ...
Yu S, Zhang Q, Su L, He J, Shi W, Yan H, Mao H, Sun Y, Cheng D, Wang X, Zhang Y, Fang L.   +11 more
europepmc   +3 more sources

Field-deployable, ultrasensitive and visual detection systems targeting severe fever with thrombocytopenia syndrome virus (Dabie bandavirus) based on CRISPR/Cas12a and DNAzyme. [PDF]

Clin Transl Med
Clinical and Translational Medicine, Volume 15, Issue 7, July 2025.
Wang J, Yue M, Mao Y, Chen Q, Ge Y, Yi H, Wang H, Yang S, Zhu J, Li Y, Qi Y.   +10 more
europepmc   +5 more sources

Susceptibility of Type I Interferon Receptor Knock-Out Mice to Heartland Bandavirus (HRTV) Infection and Efficacy of Favipiravir and Ribavirin in the Treatment of the Mice Infected with HRTV

Viruses, 2022
Heartland bandavirus (HRTV) is an emerging tick-borne virus that is distributed in the United States and that causes febrile illness with thrombocytopenia and leukocytopenia.
Hikaru Fujii, Hideki Tani, Kazutaka Egawa, Satoshi Taniguchi, Tomoki Yoshikawa, Shuetsu Fukushi, Souichi Yamada, Shizuko Harada, Takeshi Kurosu, Masayuki Shimojima, Takahiro Maeki, Chang-Kweng Lim, Mutsuyo Takayama-Ito, Takashi Komeno, Nozomi Nakajima, Yousuke Furuta, Akihiko Uda, Shigeru Morikawa, Masayuki Saijo   +18 more
doaj   +2 more sources

Residual and Late Onset Symptoms Appeared in a Patient with Severe Fever with Thrombocytopenia in a Convalescence Stage

Viruses, 2021
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease caused by Dabie bandavirus (formerly SFTS virus, SFTSV). Its manifestations during the convalescent phase have not been widely described.
Kohei Kanda, Noriko Kinoshita, Satoshi Kutsuna, Keiji Nakamura, Ayako Okuhama, Akira Shimomura, Takeshi Inagaki, Tomoki Yoshikawa, Takeshi Kurosu, Masayuki Shimojima, Masayuki Saijo, Norio Ohmagari   +11 more
doaj   +2 more sources

Recombinant Dabie bandavirus as a bivalent vaccine platform inducing protective immunity against intracellular pathogens and cancer. [PDF]

Mol Ther
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne pathogen endemic to East Asia, associated with high mortality and lacking approved vaccines or therapies. We developed a live-attenuated vaccine platform based on a recombinant SFTSV, which lacks the nonstructural protein on the S segment (NSs) gene, a key virulence ...
Ro HJ, Lee Y, Jeon K, Kim Y, Baek SH, Kim G, Kim J, Kang JG, Jang NY, Lee SH, Kim SY, Kim YJ, Ha NY, Kim Y, Choi YK, Jung JU, Hong JJ, Cho NH.   +17 more
europepmc   +3 more sources

<i>Dabie bandavirus</i> Nonstructural Protein Interacts with Actin to Induce F-Actin Rearrangement and Inhibit Viral Adsorption and Entry. [PDF]

J Virol, 2022
Dabie bandavirus (DBV), a member of the Phenuiviridae family, is a newly emerging tick-borne pathogen that causes multifunctional organ failure and even death in humans. The actin cytoskeleton is involved in various crucial cellular processes and plays an important role in viral life activities.
Liu H, Liu S, Liu Z, Gao X, Xu L, Huang M, Su Y, Wang Z, Wang T.   +8 more
europepmc   +3 more sources

Phylogeographic epidemiology of Dabie bandavirus in East Asia: divergent transmission networks and genotype‑linked clinical severity [PDF]

Infectious Diseases of Poverty
Background Severe fever with thrombocytopenia syndrome (SFTS), caused by Dabie bandavirus (SFTSV), exhibits geographically decoupled incidence and fatality patterns across East Asia.
Letian Fang, Jiluo Liu, Jimin Sun, Ping Li, Zhongfa Wang, Hongxia Ni, Ling Ye, Yiwei Shi, Xin Yang, Hanzheng Mu, Peng Li, Yibo Ding, Xiaojie Tan, Jianhua Yin, Wei Liu, Guangwen Cao   +15 more
doaj   +2 more sources