Results 21 to 30 of about 542 (103)

Dabie bandavirus identified from patients with severe fever with thrombocytopenia syndrome in northwestern of Hubei Province, China, 2024 [PDF]

Frontiers in Public Health
IntroductionSevere fever with thrombocytopenia syndrome (SFTS), caused by Dabie bandavirus (DBV), is a zoonotic disease characterized by substantial mortality. Hubei Province is an epidemic region with a high incidence rate of SFTS.
Mengzhu Zhang, Peixi Fu, ZhongJi Meng, Yuqian He, Xueqin Qin, Sen Luo, Yunzhen Xu, Li Liu, Guangyu Qiu, Yang Liu, Yanli Peng, Fangmin Song, Tianyi Xu, Jiao Yin, Mingming Liu, Chuanmin Wang   +15 more
doaj   +4 more sources

Multi-Epitope mRNA Vaccine Targeting Glycoprotein: An Immunoinformatics-Based Study [PDF]

Bioinformatics and Biology Insights
Dabie bandavirus (DBV), also called severe fever with thrombocytopenia syndrome virus (SFTSV), is a tick-borne virus that leads to a serious illness with high fever, low platelets, bleeding risks, and organ damage.
Sk Faisal Ahmed, Md Shah Paran, Md Masudur Rahman Munna, Enam Ahmed, Upom Majumder, Monisha Rahmatullah, Md Zulfekar Ali   +6 more
doaj   +3 more sources

Host factor MxA restricts Dabie bandavirus infection by targeting the viral NP protein to inhibit NP-RdRp interaction and ribonucleoprotein activity [PDF]

Journal of Virology
ABSTRACT Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease with high case mortality rates, which is caused by Dabie bandavirus (DBV), a novel pathogen also termed as SFTS virus (SFTSV). Currently, no specific therapeutic drugs or vaccines are available for SFTS.
Yun-Jia Ning, Hualin Wang, Yuan-Qin Min   +2 more
exaly   +4 more sources

The molecular evolution of Dabie bandavirus (Phenuiviridae: Bandavirus: Dabie bandavirus), the agent of severe fever with thrombocytopenia syndrome

Вопросы вирусологии, 2022
Since the Dabie bandavirus (DBV; former SFTS virus, SFTSV) was identified, the epidemics of severe fever with thrombocytopenic syndrome (SFTS) caused by this virus have occurred in several countries in East Asia. The rapid increase in incidence indicates
T. E. Sizikova, V. N. Lebedev, S. V. Borisevich   +2 more
doaj   +4 more sources

Dabie bandavirus infection induces macrophagic pyroptosis and this process is attenuated by platelets. [PDF]

PLoS Negl Trop Dis, 2023
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infection with a high mortality rate in humans, which is caused by Dabie bandavirus (DBV), formerly known as SFTS virus. Clinical manifestations of SFTS are characterized by high fever, thrombocytopenia, leukopenia, hemorrhage, gastrointestinal symptoms, myalgia and local ...
Yu S, Zhang Q, Su L, He J, Shi W, Yan H, Mao H, Sun Y, Cheng D, Wang X, Zhang Y, Fang L.   +11 more
europepmc   +3 more sources

<i>Dabie bandavirus</i> Nonstructural Protein Interacts with Actin to Induce F-Actin Rearrangement and Inhibit Viral Adsorption and Entry. [PDF]

J Virol, 2022
Dabie bandavirus (DBV), a member of the Phenuiviridae family, is a newly emerging tick-borne pathogen that causes multifunctional organ failure and even death in humans. The actin cytoskeleton is involved in various crucial cellular processes and plays an important role in viral life activities.
Liu H, Liu S, Liu Z, Gao X, Xu L, Huang M, Su Y, Wang Z, Wang T.   +8 more
europepmc   +3 more sources

An integrated surveillance in Zhejiang Province: ecological and pathogen survey of vectors and reservoir hosts in 2024 [PDF]

Frontiers in Veterinary Science
IntroductionIn this study, an integrated surveillance framework was employed to simultaneously quantify the population densities of key vectors and reservoir hosts and screen them for associated pathogens across Zhejiang Province, China.MethodsThe light ...
Jinna Wang, Mingyu Luo, Qinmei Liu, Tianqi Li, Zhou Guan, Zhenyu Gong, Juan Hou, Jimin Sun, Jianmin Jiang   +8 more
doaj   +2 more sources

Human-to-Human Transmission of Severe Fever With Thrombocytopenia Syndrome Resulting in Fatal Cases: A Case Series. [PDF]

Case Rep Infect Dis
Severe fever with thrombocytopenia syndrome (SFTS), primarily a tick‐borne disease, can also cause fatal human‐to‐human transmission. This report analyzes a cluster of six SFTS cases identified in China in 2022, involving one index patient and five secondary infections, with an overall mortality of 83%.
Yao L, Yang X, Gao X, Yuan Y, Li C, Gao C, Shu H, Zou X, Li R, Xu J, Shang Y.   +10 more
europepmc   +2 more sources

Characterization of high-affinity antibodies against the surface Gc protein of Dabie bandavirus / severe fever with thrombocytopenia syndrome virus. [PDF]

Biochem Biophys Rep
Severe fever with thrombocytopenia syndrome virus (SFTSV) or Dabie bandavirus is an emerging pathogen responsible for SFTS. It is considered a novel threat to human health, given the high associated fatality. SFTSV is a segmented negative-strand RNA virus containing three single-stranded RNAs, with the M segment encoding the glycoproteins Gn and Gc. Gc
Jeon P, Yoo B, Kim Y, Lee SY, Woo HM, Lim HY, Lee JY, Park S, Lee H.   +8 more
europepmc   +4 more sources

Computer-aided designing of a novel multi‑epitope DNA vaccine against severe fever with thrombocytopenia syndrome virus [PDF]

BMC Infectious Diseases
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne viral disease caused by the SFTS virus (Dabie bandavirus), which has become a substantial risk to public health.
Yiran Tao, Yu Zhang, Yumeng Li, Qiao Liu, Jin Zhu, Minjun Ji, Gaoqian Feng, Zhipeng Xu   +7 more
doaj   +2 more sources