Results 51 to 60 of about 28,958 (244)

Possible Interaction between Dabigatran and Ranolazine in Patients with Renal Failure

Medicina, 2019
Dabigatran etexilate is a direct oral anticoagulant (thrombin inhibitor) used for the prevention of stroke and systemic thromboembolic events in patients with permanent atrial fibrillation; prevention of venous thromboembolic events and deep veins ...
Gintautas Gumbrevičius, Gytė Damulevičienė, Vaidotas Galaunė, Milda Gumbrevičiūtė   +3 more
doaj   +1 more source

Safety of dabigatran etexilate for the secondary prevention of venous thromboembolism in children.

Blood, 2019
This open-label, single-arm, prospective cohort trial is the first phase 3 safety study to describe outcomes in children treated with dabigatran etexilate for secondary venous thromboembolism (VTE) prevention. Eligible children aged 12 to
L. Brandão, M. Albisetti, J. Halton, L. Bomgaars, E. Chalmers, L. Mitchell, I. Nurmeev, P. Svirin, T. Kuhn, O. Zapletal, I. Tartakovsky, Monika Simetzberger, F. Huang, Zhichao Sun, J. Kreuzer, S. Gropper, M. Brueckmann, M. Luciani   +17 more
semanticscholar   +1 more source

The Protective Effect of Dabigatran and Rivaroxaban on DNA Oxidative Changes in a Model of Vascular Endothelial Damage with Oxidized Cholesterol

International Journal of Molecular Sciences, 2020
Background: Atherosclerotic plaques are unstable, and their release may result in thrombosis; therefore, currently, antiplatelet therapy with anticoagulants is recommended for the treatment of acute coronary syndrome.
E. Woźniak, M. Broncel, B. Bukowska, P. Gorzelak-Pabiś   +3 more
semanticscholar   +1 more source

The Impact of a Visualized Steerable Sheath on Radiofrequency Catheter Ablation for First‐Time Atrial Fibrillation Ablation: A Prospective, Randomized, Single‐Blind Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background A 3D electroanatomical mapping (3D‐EAM) visualized steerable sheath was designed to improve catheter placement and reduce radiation exposure during ablation, an established treatment for atrial fibrillation (AF). However, prospective randomized data comparing the procedural and clinical outcomes of visualized and non‐visualized ...
Chun‐Kai Chen, Chih‐Chieh Yu, Min‐Tsun Liao, Hui‐Chun Huang, Yen‐Bin Liu   +4 more
wiley   +1 more source

DABIGATRAN

Journal of Prescribing Practice, 2020
In this column, Sharon Rees aims to refresh knowledge and interest in some of the commonly used drugs in a series of tweets. This month she is talking about #dabigatran
openaire   +2 more sources

Long-term dabigatran treatment delays Alzheimer’s disease pathogenesis in the TgCRND8 mouse model

Journal of the American College of Cardiology, 2019
Background – Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder with important vascular and hemostatic alterations that should be taken into account during diagnosis and treatment.
M. Cortes-Canteli, A. Kruyer, Irene Fernández-Nueda, Ana Marcos-Díaz, C. Céron, Allison T. Richards, Odella Jno-Charles, I. Rodríguez, S. Callejas, E. Norris, J. Sánchez-González, J. Ruíz-Cabello, B. Ibáñez, S. Strickland, V. Fuster   +14 more
semanticscholar   +1 more source

The Effect of Dicloxacillin Administration on Pharmacokinetics of Narrow Therapeutic Window Drugs: Phenytoin and Warfarin

Clinical Pharmacology &Therapeutics, EarlyView.
Dicloxacillin is a penicillinase‐resistant beta‐lactam antibiotic and potent activator of the Pregnane X receptor (PXR), known to induce CYP2C9, CYP2C19, and CYP3A4 activity. Clinical data suggest it reduces anticoagulation in warfarin‐treated patients and increases the risk of thromboembolic events.
Chanan Shaul, Waseem Mujahed, Ibrahim Idries, Maor Wanounou, Meir Bialer, Yoseph Caraco   +5 more
wiley   +1 more source

Hemoclot Thrombin Inhibitor Assay and Expected Peak-Trough Levels of Dabigatran: A Multicenter Study

Frontiers in Cardiovascular Medicine, 2022
PurposeDabigatran concentrations monitoring are gaining importance of special situations, but limited data are available for the expected peak and trough levels. The hemoclot thrombin inhibitor (HTI) is dabigatran-calibrated quantitative determination of
Zhiyan Liu, Guangyan Mu, Qiufen Xie, Hanxu Zhang, Hanxu Zhang, Jie Jiang, Qian Xiang, Yimin Cui, Yimin Cui, Yimin Cui   +9 more
doaj   +1 more source

Efficacy and Safety of Apixaban, Dabigatran, Rivaroxaban, and Warfarin in Asians With Nonvalvular Atrial Fibrillation

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2018
Background Whether non–vitamin K antagonist oral anticoagulants (NOACs) are superior to warfarin among Asians with nonvalvular atrial fibrillation remains unclear.
Y. Chan, L. See, H. Tu, Yung-Hsin Yeh, Shang-Hung Chang, Lung-Sheng Wu, Hsin-Fu Lee, Chun-Li Wang, Chang-Fu Kuo, C. Kuo   +9 more
semanticscholar   +1 more source

Preliminary Evaluation of a Novel Lupus Anticoagulant Activity Assay Unaffected by Anticoagulants

Journal of Clinical Laboratory Analysis, EarlyView.
A novel one‐step lupus anticoagulant (LA) assay based on the LA‐sensitivity ratio (LA‐SR) was developed to simplify diagnostic testing and reduce potential interference from anticoagulants. The LA‐SR method showed good agreement with guideline‐based LA testing (dRVVT and/or LA‐sensitive APTT) for the detection of LA and demonstrated limited influence ...
Ayu Hidaka, Risa Kaneshige, Seika Nakamura, Yukari Motoki, Junzo Nojima   +4 more
wiley   +1 more source