Results 71 to 80 of about 21,646 (232)

Pharmacogenetics of dabigatran etexilate interindividual variability [PDF]

, 2016
Introduction Dabigatran etexilate is given in fixed doses without coagulation monitoring for the prevention of blood clots in at risk adults. A high inter-individual variability in blood concentrations of the active metabolite of dabigatran has been ...
Vecchione, Gennaro, Dimatteo, Claudia, Buono, Matteo, Testa, Sophie, Grandone, Elvira, MARGAGLIONE, MAURIZIO, Cappucci, Filomena, Tiscia, Giovanni Luca, D'ANDREA, GIOVANNA, Paoletti, Oriana   +9 more
core   +1 more source

Toward the harmonization of bioequivalence guidelines in Europe: Commentary on the state of the art and future priorities under ICH M13A for immediate‐release oral forms

British Journal of Clinical Pharmacology, EarlyView.
Domenico Nocera, Giusi Forastiero, Andrea Logreco, Alessia Proietti, Antonio Galluccio, Carlotta Lunghi, Elisabetta Poluzzi, Fabrizio De Ponti   +7 more
wiley   +1 more source

Implementation of a Standardized Nurse‐Guided Heparinization Protocol Improves Anticoagulation During Left Atrial Ablation Procedures

Journal of Cardiovascular Electrophysiology, EarlyView.
A standardized, nurse‐led heparinization protocol significantly improves the speed, consistency, and precision of achieving therapeutic ACT levels during left atrial ablation, while reducing excessive anticoagulation and maintaining a comparable safety profile to conventional operator‐guided dosing.
Vanessa Sciacca, Jasmin Retzlaff, Martin Braun, Thomas Fink, Angeliki Darma, Yuri Bocchini, Karen Harutyunyan, Philipp Lucas, Nadica Trajkovksa, Denise Guckel, Moneeb Khalaph, Maximilian Moersdorf, Maxim Didenko, Christian Sohns, Philipp Sommer   +14 more
wiley   +1 more source

Primary cardiovascular preventive effect of thiazolidinedione in adults with type 2 diabetes: A nationwide cohort study in Korea

Journal of Diabetes Investigation, EarlyView.
Among Korean adults with type 2 diabetes and no prior cardiovascular disease, thiazolidinedione use was associated with a lower risk of the primary composite outcome of stroke, myocardial infarction, hospitalization for heart failure, and all‐cause mortality compared to dipeptidyl peptidase‐4 inhibitor use. ABSTRACT Background Thiazolidinediones (TZDs)
Yun Young Choi, Jimin Jeon, Minyoul Baik, Joonsang Yoo, Jinkwon Kim   +4 more
wiley   +1 more source

Personalizing the decision of dabigatran versus warfarin in atrial fibrillation: A secondary analysis of the Randomized Evaluation of Long-term anticoagulation therapY (RE-LY) trial.

PLoS ONE, 2021
BackgroundThe RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) trial demonstrated that higher-risk patients with atrial fibrillation had lower rates of stroke or systemic embolism and a similar rate of major bleeding, on average, when ...
Samuel W Reinhardt, Nihar R Desai, Yuanyuan Tang, Philip G Jones, Jeremy Ader, John A Spertus   +5 more
doaj   +1 more source

Dapagliflozin does not impair microvascular hemorheology in type 2 diabetes mellitus: A multicenter randomized controlled trial (D‐PATH study)

Journal of Diabetes Investigation, EarlyView.
Graphical abstract illustrating the study design, physiological rationale, and key findings of the D‐PATH trial. Dapagliflozin, an SGLT2 inhibitor, lowers HbA1c and body weight while increasing hematocrit and erythropoietin levels. Although an elevated hematocrit could theoretically increase blood viscosity and impair microcirculatory flow, ex vivo ...
Yuki Nakatani, Nobuyuki Banba, Shoya Ono, Tomoki Turumi, Megumi Hoshiai, Takushi Sugiyama, Takashi Tomoe, Hajime Tamiya, Naoyuki Otani, Hiroyuki Sugimura, Hidekazu Ikemiyagi, Yusuke Ohya, Koji Yokokawa, Shinichiro Ueda, Yoshimasa Aso, Yasuhiro Maejima, Takanori Yasu   +16 more
wiley   +1 more source

Thrombolysis after dabigatran reversal

, 2022
Protocol for a systematic review on safety and efficacy of thrombolysis after dabigatran reversal with ...
Michele Romoli
core   +2 more sources

Dabigatran experience in primary and secondary prevention of cardioembolic stroke

Неврология, нейропсихиатрия, психосоматика, 2013
The review of novel oral anticoagulants (dabigatran, rivaroxaban and apixaban) in stroke prevention and also own data of administration of dabigatran in primary and secondary prevention of ischemic stroke in 45 patients with cerebrovascular diseases are ...
Maksim Alekseyevich Domashenko, M Yu Maksimova, D Z Korobkova, M E Gafarova   +3 more
doaj   +1 more source

Percutaneous Sclerotherapy for Giant Hepatic Haemangiomas: A New Paradigm in Australia

ANZ Journal of Surgery, EarlyView.
Warren Clements, Tim Joseph, Stuart K. Roberts, Kaye Bowers   +3 more
wiley   +1 more source

Early Mobilization After Pacemaker Implantation

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background The increasing use of cardiac implantable electronic devices (CIED) is leading to a rise in procedure‐related complications. Objective This trial aimed to assess the safety and feasibility of early mobilization and the possibility of same‐day discharge following permanent pacemaker implantation.
Jiří Šmíd, Vlastimil Vančura, Martin Brada, Richard Rokyta   +3 more
wiley   +1 more source