Results 31 to 40 of about 8,933 (160)

Dabigatran versus Warfarin for the Treatment of Pediatric Thromboembolism: A Pilot Randomized Trial [PDF]

Pharmaceutical Sciences, 2020
Background: Venous thromboembolism (VTE) is still a problematic situation in children. Drugs like warfarin, enoxaparin, and heparin are current standard of care in childhood VTE. This study was designed to compare the efficacy of warfarin with dabigatran
Aziz Eghbali, Roghayyeh Rahimi Afzal, Roya Sheikhbeygloo, Aygin Eghbali, Bahar Taherkhanchi, Bahador Bagheri   +5 more
doaj   +1 more source

New safety standards for anticoagulant therapy in the treatment of atrial fibrillation

Российский кардиологический журнал, 2018
The review article study the safety and efficacy of using direct acting oral anticoagulants: thrombin inhibitor dabigatran etexilate and inhibitors Xa of the blood clotting factor apixaban, rivaroxaban and edoxaban compared with the vitamin K antagonist ...
E. I. Baranova
doaj   +1 more source

Adverse events in patients initiated on dabigatran etexilate therapy in a pharmacist-managed anticoagulation clinic [PDF]

, 2013
Background: Vitamin K antagonists have been the treatment of choice in preventing thromboembolic events, but problems such as frequent dose adjustment and monitoring of coagulation status, including multiple drug and food interactions, make their use ...
Norbeck AO, Donaldson M
core   +2 more sources

Dabigatran Etexilate: A Review in Pediatric Venous Thromboembolism

, 2022
Declarations Funding The preparation of this review was not supported by any external funding. Authorship and Conflict of interest Julia Paik is a salaried employee of Adis International Ltd/Springer Nature, and declares no relevant conflicts of interest.
Julia Paik (6912664)
core   +1 more source

Investigation of Solid-State Hydrate-Anhydrous Phase Transformations of Dabigatran Etexilate Hemi-Edisylate

Crystals, 2023
In this study, a dabigatran etexilate edisylate (DBE) was prepared by the reaction crystallization of dabigatran etexilate (DBG) and edisilic acid. According to single crystal X-ray diffraction (SXRD), it was revealed that two DGB were combined with one ...
Jin Feng, Changjin Lim, Sihyun Nam, Woojin Yoon, Hoseop Yun, Woo-Sik Kim, Ji-Hun An   +6 more
doaj   +1 more source

Dabigatran of etexilate (paradox®) for the patients with closed diaphyseal fractures of the femur and tibia

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2014
The results of application of dabigatran etexilate in treatment of 56 patients aged 60 to 89 with closed diaphyseal fractures of femur and tibia undergone intramedullary osteosynthesis were studied. The patients were divided into 2 groups.
A. K. Dulaev, A. N. Tsed, I. G. Dzhusoev
doaj   +1 more source

The development and validation of analytical methods for the quantitative determination of dabigatran etexilate by HPLC-DAD and UV spectrophotometry during a comparative dissolution kinetics test of dabigatran capsules in the biorelevant FaSSGF medium

Разработка и регистрация лекарственных средств
Introduction. Venous thromboembolism and atrial fibrillation are significant causes of vascular mortality. Anticoagulant therapy significantly reduces the risk of ischemic stroke, and dabigatran etexilate, a direct thrombin inhibitor, has become firmly ...
D. M. Devyatkina, P. S. Mashchenko, A. D. Vnutskikh, I. O. Devyatkin, N. A. Prozorova, A. V. Foteeva   +5 more
doaj   +1 more source

Dabigatran etexilate tetrahydrate

Acta Crystallographica Section E, 2012
In the title compound, C34H41N7O5·4H2O (systematic name: ethyl 3-{[2-({4-[(Z)-amino(hexyloxycarbonylimino)methyl]anilino}methyl)-1-methylbenzimidazole-5-carbonyl]pyridin-2-ylamino}propanoate tetrahydrate), the benzene and pyridine rings form ...
Hong-Qiang Liu, Wei-Guang Zhang, Zhi-Qiang Cai, Wei-Ren Xu, Xiu-Ping Shen   +4 more
doaj   +1 more source

Comparative differences in the risk of major gastrointestinal bleeding among different direct oral anticoagulants: An updated traditional and Bayesian network meta-analysis

Frontiers in Pharmacology, 2023
Background: The most favorable gastrointestinal (GI) bleeding safety profile among different types of direct oral anticoagulants (DOACs) remains controversial. This meta-analysis includes the latest studies and aims to compare GI bleeding risk associated
Xiuehui Chen, Lili Wang, Huijun Li, Weichao Huang, Lingyue Zhao, Wenqin Guo   +5 more
doaj   +1 more source

Current practice and guideline adherence in renal dose adjustment for patients with chronic kidney disease: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed, Ahmed Tehemar, Mohamed Gasimelseed, Ahmed Gharaibeh, Muhammad Abdul Hadi, Kazeem Yusuff, Amani Zidan, Ahmed Awaisu   +7 more
wiley   +1 more source